The field of cancer nanomedicine seeks to overcome the inherent shortcomings of
conventional cancer diagnostics and therapies. Yet despite the surge of interest in and …

Extracellular vesicles (EVs) have increasingly been recognized as important cell surrogates
influencing many pathophysiological processes, including cellular homeostasis, cancer …

Near‐infrared (NIR) chemiluminescence imaging holds potential for sensitive imaging of
cancer due to its low background; however, few NIR chemiluminophores are available …

Cancer mortality is exacerbated by late-stage diagnosis. Liquid biopsies based on genomic
biomarkers can noninvasively diagnose cancers. However, validation studies have …

Protein profiles of exosomes (EXOs) in clinical samples of cancer patients have become a
promising diagnostic and therapeutic biomarker. However, simultaneous quantitative …

Exosomes are membrane-defined extracellular vesicles (EVs) approximately 40–160​ nm
in diameter that are found in all body fluids including blood, urine, and saliva. They act as …

Enhanced imaging techniques using contrast agents enable high-resolution structural
imaging to reveal space-occupying lesions but rarely provide detailed molecular …

The earliest events during human tumour initiation, although poorly characterized, may hold
clues to malignancy detection and prevention. Here we model occult preneoplasia by …

Imaging of tumor-associated microRNAs (miRNAs) can provide abundant information for
cancer diagnosis, whereas the occurrence of trace amounts of miRNAs in normal cells …

Extrachromosomal circular DNA (eccDNA) is defined as a type of circular DNA that exists
widely in nature and is independent of chromosomes. EccDNA has attracted the attention of …