Major depressive disorder (MDD), also referred to as depression, is one of the most common
psychiatric disorders with a high economic burden. The etiology of depression is still not …

Currently, over 300 million people worldwide have depression, and the socioeconomic
burden of this debilitating disorder is anticipated to increase markedly over the coming …

Network Medicine applies network science approaches to investigate disease
pathogenesis. Many different analytical methods have been used to infer relevant molecular …

Major depressive disorder (MDD) is a common, debilitating, phenotypically heterogeneous
disorder with heritability ranges from 30% to 50%. Compared to other psychiatric disorders …

Depression is a heterogeneous and etiologically complex psychiatric syndrome, not a
unitary disease entity, encompassing a broad spectrum of psychopathology arising from …

Major depressive disorder is a remarkably common and often severe psychiatric disorder
associated with high levels of morbidity and mortality. Patients with major depression are …

The prevalence and clinical characteristics of depressive disorders differ between women
and men; however, the genetic contribution to sex differences in depressive disorders has …

Structural and functional brain alterations are common in patients with major depressive
disorder (MDD). In this review, we assessed the recent literature (1995–2018) on the …

Depression is a highly heterogeneous syndrome that bears only modest correlations with its
biological substrates, motivating a renewed interest in rethinking our approach to …

Background A large body of research has reported associations between depression and
elevated interleukin-6 (IL-6), a cytokine with several roles including pro-inflammatory …