Detrimental effects of lipid peroxidation in type 2 diabetes: Exploring the neutralizing influence of antioxidants

SC Shabalala, R Johnson, AK Basson, K Ziqubu… - Antioxidants, 2022 - mdpi.com
Lipid peroxidation, including its prominent byproducts such as malondialdehyde (MDA) and
4-hydroxy-2-nonenal (4-HNE), has long been linked with worsened metabolic health in …

The role of PKC-MAPK signalling pathways in the development of hyperglycemia-induced cardiovascular complications

FF Jubaidi, S Zainalabidin, IS Taib… - International Journal of …, 2022 - mdpi.com
Cardiovascular disease is the most common cause of death among diabetic patients
worldwide. Hence, cardiovascular wellbeing in diabetic patients requires utmost importance …

[HTML][HTML] Phytochemical analysis and evaluation of antimicrobial, antioxidant, and antidiabetic activities of essential oils from Moroccan medicinal plants: Mentha …

N El Hachlafi, N Benkhaira, SH Al-Mijalli… - Biomedicine & …, 2023 - Elsevier
Mentha suaveolens, Lavandula stoechas, and Ammi visnaga are widely used in Moroccan
folk medicine against several pathological disorders, including diabetes and infectious …

Exploring the complex relationship between diabetes and cardiovascular complications: understanding diabetic cardiomyopathy and promising therapies

N Ghosh, L Chacko, H Bhattacharya, J Vallamkondu… - Biomedicines, 2023 - mdpi.com
Diabetes mellitus (DM) and cardiovascular complications are two unmet medical
emergencies that can occur together. The rising incidence of heart failure in diabetic …

Therapeutic Potential of Hibiscus sabdariffa Linn. in Attenuating Cardiovascular Risk Factors

S Sapian, AA Ibrahim Mze, FF Jubaidi, NA Mohd Nor… - Pharmaceuticals, 2023 - mdpi.com
Cardiovascular diseases (CVDs) represent a broad spectrum of diseases afflicting the heart
and blood vessels and remain a major cause of death and disability worldwide. CVD …

An overview of the cardioprotective effects of novel antidiabetic classes: focus on inflammation, oxidative stress, and fibrosis

DB Balogh, LJ Wagner, A Fekete - International Journal of Molecular …, 2023 - mdpi.com
Metabolic diseases, particularly diabetes mellitus (DM), are significant global public health
concerns. Despite the widespread use of standard-of-care therapies, cardiovascular disease …

Antidiabetic properties of plant secondary metabolites

S Sukhikh, O Babich, A Prosekov, O Kalashnikova… - Metabolites, 2023 - mdpi.com
The prevalence of diabetes mellitus is one of the major medical problems that the modern
world is currently facing. Type 1 and Type 2 diabetes mellitus both result in early disability …

Dihydromyricetin attenuates diabetic cardiomyopathy by inhibiting oxidative stress, inflammation and necroptosis via sirtuin 3 activation

Y Chen, Y Zheng, R Chen, J Shen, S Zhang, Y Gu… - Antioxidants, 2023 - mdpi.com
Dihydromyricetin (DHY), the main flavonoid component in Ampelopsis grossedentata, has
important benefits for health. The present study aimed to investigate the exact effects and …

Diabetic cardiomyopathy–Zinc preventive and therapeutic potentials by its anti-oxidative stress and sensitizing insulin signaling pathways

L Cai, Y Tan, S Watson, K Wintergerst - Toxicology and applied …, 2023 - Elsevier
Oxidative stress and insulin resistance are two key mechanisms for the development of
diabetic cardiomyopathy (DCM, cardiac remodeling and dysfunction). In this review, we …

What is the impact of ferroptosis on diabetic cardiomyopathy: a systematic review

X Lou, Y Zhang, J Guo, L Gao, Y Ding, X Zhuo… - Heart Failure …, 2023 - Springer
Iron overload increases the production of harmful reactive oxygen species in the Fenton
reaction, which causes oxidative stress in the body and lipid peroxidation in the cell …