Preventive strategies for cognitive decline and dementia: benefits of aerobic physical activity, especially open-skill exercise

T Yamasaki - Brain Sciences, 2023 - mdpi.com
As there is no curative treatment for dementia, including Alzheimer's disease (AD), it is
important to establish an optimal nonpharmaceutical preventive intervention. Physical …

Fecal microbiota transplantation: A novel strategy for treating Alzheimer's disease

W Xiang, H Xiang, J Wang, Y Jiang, C Pan… - Frontiers in …, 2023 - frontiersin.org
Alzheimer's disease is a common neurological disorder, which has become one of the major
factors affecting human health due to its serious impact on individuals, families and society …

Prevalence of dementia in India: National and state estimates from a nationwide study

J Lee, E Meijer, KM Langa, M Ganguli… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Prior estimates of dementia prevalence in India were based on samples from
selected communities, inadequately representing the national and state populations …

Expected and diagnosed rates of mild cognitive impairment and dementia in the US Medicare population: observational analysis

S Mattke, H Jun, E Chen, Y Liu, A Becker… - Alzheimer's Research & …, 2023 - Springer
Background With the emergence of disease-modifying Alzheimer's treatments, timely
detection of early-stage disease is more important than ever, as the treatment will not be …

NREM sleep as a novel protective cognitive reserve factor in the face of Alzheimer's disease pathology

Z Zavecz, VD Shah, OG Murillo, R Vallat, BA Mander… - BMC medicine, 2023 - Springer
Background Alzheimer's disease (AD) pathology impairs cognitive function. Yet some
individuals with high amounts of AD pathology suffer marked memory impairment, while …

Donanemab for Alzheimer disease—who benefits and who is harmed?

JJ Manly, KD Deters - JAMA, 2023 - jamanetwork.com
Availability of safe and effective treatmentsfor Alzheimer disease is an urgent challenge
given the global shift toward an older population and increased risk of mild cognitive …

Relationships of cognitive measures with cerebrospinal fluid but not imaging biomarkers of Alzheimer disease vary between Black and white individuals

S Bonomi, R Lu, SE Schindler, Q Bui, JJ Lah… - Annals of …, 2024 - Wiley Online Library
Objective Biomarkers of Alzheimer disease vary between groups of self‐identified Black and
White individuals in some studies. This study examined whether the relationships between …

Prevalence of DSM-5 mild and major neurocognitive disorder in India: Results from the LASI-DAD

AL Gross, E Nichols, M Angrisani, M Ganguli, H Jin… - Plos one, 2024 - journals.plos.org
Introduction India, with its rapidly aging population, faces an alarming burden of dementia.
We implemented DSM-5 criteria in large-scale, nationally representative survey data in India …

State-level indicators of childhood educational quality and incident dementia in older Black and White adults

Y Soh, RA Whitmer, ER Mayeda, MM Glymour… - JAMA …, 2023 - jamanetwork.com
Importance Higher educational attainment is associated with reduced dementia risk, but the
role of educational quality is understudied, presenting a major evidence gap, especially as it …

Nasal administration of anti-CD3 monoclonal antibody ameliorates disease in a mouse model of Alzheimer's disease

JR Lopes, X Zhang, J Mayrink… - Proceedings of the …, 2023 - National Acad Sciences
Emerging evidence suggests that dysregulation of neuroinflammation, particularly that
orchestrated by microglia, plays a significant role in the pathogenesis of Alzheimer's disease …