During fertilization, the egg and the sperm are supposed to contribute precisely one copy of
each chromosome to the embryo. However, human eggs frequently contain an incorrect …

Human female fertility and reproductive lifespan decrease significantly with age, resulting in
an extended post-reproductive period. The central dogma in human female reproduction …

Accurate chromosome segregation during meiosis is crucial for reproduction. Human and
porcine oocytes transiently cluster their chromosomes before the onset of spindle assembly …

Meiotic spindle assembly ensures proper chromosome segregation in oocytes. However,
the mechanisms behind spindle assembly in human oocytes remain largely unknown. We …

Error-free chromosome segregation in mitosis and meiosis relies on the assembly of a
microtubule-based spindle that interacts with kinetochores to guide chromosomes to the cell …

Meiosis, a key process in the creation of haploid gametes, is a complex cellular division
incorporating unique timing and intricate chromosome dynamics. Abnormalities in this …

Background: Twelve separate streams of empirical data make a strong case for cannabis-
induced accelerated aging including hormonal, mitochondriopathic, cardiovascular …

Meiotic maturation is an intricate and precisely regulated process orchestrated by various
pathways and numerous proteins. However, little is known about the proteome landscape …

Cilia and mitotic spindles are microtubule (MT)-based, macromolecular machines that
consecutively assemble and disassemble during interphase and M phase of the cell cycle …

A large body of evidence indicates that women with polycystic ovary syndrome (PCOS) have
a higher risk of developing Hashimoto's thyroiditis (HT) than healthy individuals. Given the …