Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies

M Solmi, J Radua, M Olivola, E Croce, L Soardo… - Molecular …, 2022 - nature.com
Promotion of good mental health, prevention, and early intervention before/at the onset of
mental disorders improve outcomes. However, the range and peak ages at onset for mental …

The link between schizophrenia and substance use disorder: A unifying hypothesis

JY Khokhar, LL Dwiel, AM Henricks, WT Doucette… - Schizophrenia …, 2018 - Elsevier
Substance use disorders occur commonly in patients with schizophrenia and dramatically
worsen their overall clinical course. While the exact mechanisms contributing to substance …

Daily use, especially of high-potency cannabis, drives the earlier onset of psychosis in cannabis users

M Di Forti, H Sallis, F Allegri, A Trotta… - Schizophrenia …, 2014 - academic.oup.com
Cannabis use is associated with an earlier age of onset of psychosis (AOP). However, the
reasons for this remain debated. Methods: We applied a Cox proportional hazards model to …

Gone to pot–a review of the association between cannabis and psychosis

R Radhakrishnan, ST Wilkinson, DC D'Souza - Frontiers in psychiatry, 2014 - frontiersin.org
Cannabis is the most commonly used illicit drug worldwide, with~ 5 million daily users
worldwide. Emerging evidence supports a number of associations between cannabis and …

Interactions between variation in candidate genes and environmental factors in the etiology of schizophrenia and bipolar disorder: a systematic review

B Misiak, F Stramecki, Ł Gawęda, K Prochwicz… - Molecular …, 2018 - Springer
Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with
high heritability rates. The contribution of genetic factors to the etiology of these disorders is …

Cannabis use in adolescence and risk of psychosis: Are there factors that moderate this relationship? A systematic review and meta-analysis

SK Kiburi, K Molebatsi, V Ntlantsana… - Substance …, 2021 - journals.sagepub.com
Background Previous research has reported increased risk for psychosis among individuals
who use cannabis during adolescence. We conducted a systematic review and meta …

Gene–environment interplay in the etiology of psychosis

A Zwicker, EM Denovan-Wright, R Uher - Psychological medicine, 2018 - cambridge.org
Schizophrenia and other types of psychosis incur suffering, high health care costs and loss
of human potential, due to the combination of early onset and poor response to treatment …

Responding to challenges for people with psychotic illness: Updated evidence from the Survey of High Impact Psychosis

VA Morgan, A Waterreus, V Carr… - Australian & New …, 2017 - journals.sagepub.com
Objective: The objective is to summarise recent findings from the 2010 Australian Survey of
High Impact Psychosis (SHIP) and examine their implications for future policy and planning …

Clinical characteristics and predictors of outcome of schizophrenia-spectrum psychosis in children and adolescents: a systematic review

M Stentebjerg-Olesen, AK Pagsberg… - Journal of Child and …, 2016 - liebertpub.com
Objective: Treatment of early-onset schizophrenia spectrum psychosis (EOS) is hampered
by limited data on clinical presentation and illness course. We aimed to systematically …

Adolescent cannabis use and later development of schizophrenia: An updated systematic review of longitudinal studies

SL Godin, S Shehata - Journal of clinical psychology, 2022 - Wiley Online Library
Background The study aimed to review recent literature not included in previous reviews
and ascertain the correlation between early marijuana use among adolescents, between 12 …