[HTML][HTML] Selected biomarkers of depression: what are the effects of cytokines and inflammation?

S Harsanyi, I Kupcova, L Danisovic, M Klein - International journal of …, 2022 - mdpi.com
Depression is one of the leading mental illnesses worldwide and lowers the quality of life of
many. According to WHO, about 5% of the worldwide population suffers from depression …

[HTML][HTML] The effects of dietary advanced glycation End-products on neurocognitive and mental disorders

NM D'cunha, D Sergi, MM Lane, N Naumovski… - Nutrients, 2022 - mdpi.com
Advanced glycation end products (AGEs) are glycated proteins or lipids formed
endogenously in the human body or consumed through diet. Ultra-processed foods and …

Inflammation and brain structure in schizophrenia and other neuropsychiatric disorders: a Mendelian randomization study

JA Williams, S Burgess, J Suckling, PA Lalousis… - JAMA …, 2022 - jamanetwork.com
Importance Previous in vitro and postmortem research suggests that inflammation may lead
to structural brain changes via activation of microglia and/or astrocytic dysfunction in a range …

An atlas of genetic correlations and genetically informed associations linking psychiatric and immune-related phenotypes

DS Tylee, YK Lee, FR Wendt, GA Pathak… - JAMA …, 2022 - jamanetwork.com
Importance Certain psychiatric and immune-related disorders are reciprocal risk factors.
However, the nature of these associations is unclear. Objective To characterize the …

The IL-2A receptor pathway and its role in lymphocyte differentiation and function

Y Li, X Li, X Geng, H Zhao - Cytokine & Growth Factor Reviews, 2022 - Elsevier
Murine myeloid cells are developed from hemopoietic stem/progenitor cells. Different types
of progenitor cells have variable differentiation potentials. Among the ten main types of cells …

[HTML][HTML] Major depressive disorder: Existing hypotheses about pathophysiological mechanisms and new genetic findings

M Kamran, F Bibi, A ur. Rehman, DW Morris - Genes, 2022 - mdpi.com
Major depressive disorder (MDD) is a common mental disorder generally characterized by
symptoms associated with mood, pleasure and effectiveness in daily life activities. MDD is …

[HTML][HTML] Applications of Mendelian randomization in psychiatry: a comprehensive systematic review

LF Saccaro, S Gasparini, G Rutigliano - Psychiatric Genetics, 2022 - ncbi.nlm.nih.gov
Psychiatric diseases exact a heavy socioeconomic toll, and it is particularly difficult to identify
their risk factors and causative mechanisms due to their multifactorial nature, the limited …

[HTML][HTML] Neurobiologically based stratification of recent-onset depression and psychosis: identification of two distinct transdiagnostic phenotypes

PA Lalousis, L Schmaal, SJ Wood, RLEP Reniers… - Biological …, 2022 - Elsevier
Background Identifying neurobiologically based transdiagnostic categories of depression
and psychosis may elucidate heterogeneity and provide better candidates for predictive …

[HTML][HTML] Mendelian randomization analyses in ocular disease: a powerful approach to causal inference with human genetic data

J Li, C Li, Y Huang, P Guan… - Journal of …, 2022 - … -medicine.biomedcentral.com
Ophthalmic epidemiology is concerned with the prevalence, distribution and other factors
relating to human eye disease. While observational studies cannot avoid confounding …

[HTML][HTML] The human physiology of well-being: A systematic review on the association between neurotransmitters, hormones, inflammatory markers, the microbiome …

LP de Vries, MP van de Weijer, M Bartels - Neuroscience & Biobehavioral …, 2022 - Elsevier
To understand the pathways through which well-being contributes to health, we performed a
systematic review according to the Preferred Reporting Items for Systematic Review and …