New methods for preparation of tailor-made fluorine-containing compounds are in extremely
high demand in nearly every sector of chemical industry. The asymmetric construction of …

Fluorine, often called as “a small atom with a big ego”, 1 lies in the second row and the 17th
column in the periodic table of the chemical elements. This unique position in the periodic …

Despite the growing importance of fluorinated organic compounds in drug development,
there are no direct protocols for the fluorination of aliphatic CH bonds using conveniently …

Driven by the continuous demand for optically active fluoro-containing molecules from the
chemical society, the field of fluorochemistry has emerged as a hot topic recently. While …

Organofluorine compounds 1 have found increasing applications in key industrial fields
such as the pharmaceutical 2 and medicinal chemistry 3 or crop 4 and material sciences, 5 …

The replacement of hydroxyl groups by fluorine atoms on hexopyranose scaffolds may allow
access to the discovery of new chemical entities possessing unique physical, chemical and …

Owing to the innovative applications of fluorinated compounds in many areas of technology
and medicine, methods for the preparation of C− F quaternary fluorine containing …

The first highly enantioselective α‐fluorination of 2‐acyl imidazoles utilizing iridium catalysis
has been accomplished. This transformation features mild conditions and a remarkably …

We report the first organocatalytic activation of monofluorinated silyl enol ethers 1, by
nucleophilic tertiary amine catalysis, to develop asymmetric reactions for the construction of …

Fluorinated compounds can exhibit interesting biological properties. The importance of
these species has made that the chemistry of fluorine has experienced a great development …