The search for biomarkers that quantify biological aging (particularly 'omic'-based
biomarkers) has intensified in recent years. Such biomarkers could predict aging-related …

Biological age (BA) is important for clinical monitoring and preventing aging-related
disorders and disabilities. Clinical and/or cellular biomarkers are measured and integrated …

Aging, often considered a result of random cellular damage, can be accurately estimated
using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we …

Exercise training prevents age‐related decline in muscle function. Targeting epigenetic
aging is a promising actionable mechanism and late‐life exercise mitigates epigenetic aging …

Importance Adverse childhood experiences (ACEs) are associated with the risk of poorer
health, and identifying molecular mechanisms may lay the foundation for health promotion in …

Dementia caregiving has been linked to multiple health risks, including infectious illness,
depression, anxiety, immune dysregulation, weakened vaccine responses, slow wound …

Clocks that measure biological age should predict all-cause mortality and give rise to
actionable insights to promote healthy aging. Here we applied dimensionality reduction by …

Importance Nutritive compounds play critical roles in DNA replication, maintenance, and
repair, and also serve as antioxidant and anti-inflammatory agents. Sufficient dietary intakes …

The goal of this study is to examine the association between in utero drought exposure and
epigenetic age acceleration (EAA) in a global climate change hot spot. Calculations of EAA …

Females live longer than males, and there are sex disparities in physical health and disease
incidence. However, sex differences in biological aging have not been consistently reported …