Testosterone is the predominant gonadal androgen in men. Low testosterone levels are
found to be associated with an increased in metabolic risk and systematic inflammation …

Testosterone is the predominant androgen in men and the lack of it can be a trigger to the
development of the metabolic syndrome. Here we review the relationship between …

Testosterone has historically been linked to sexual dysfunction; however, it has recently
been shown to affect other physical and mental attributes. We attempted to determine …

The nanostructure pharmaceutical formulations (NPF) which contains testosterone
undecanoate (TU) been used in life science as parent compound delivery systems for …

Testosterone replacement for older men is increasingly common, with some observations
suggesting a protective effect on cognitive function. We examined the association of …

Background: Low testosterone concentrations in men are associated with several
pathophysiological factors that affect the hypothalamic-pituitary-gonadal (HPG) axis …

Purpose The role of estrogen in cardiovascular health remains contested with discrepancies
between findings from randomized controlled trials and observational studies. Mendelian …

Objective The role of estrogen in cognitive function and depressive symptoms is
controversial due to discrepancies between results from randomized controlled trials (RCT) …

In this chapter I review the evidence that has generated the overall hypothesis explored in
this thesis: namely, that certain symptoms in Alzheimer's disease are related to systemic …

Mendelian randomisation is well known for its weak instrument bias, which is caused by the
weak genetic association with the exposure. Usually, the most significant SNP within a gene …