Impact of oral microbiome in periodontal health and periodontitis: a critical review on prevention and treatment

M Di Stefano, A Polizzi, S Santonocito… - International journal of …, 2022 - mdpi.com
The skin, oral cavity, digestive and reproductive tracts of the human body harbor symbiotic
and commensal microorganisms living harmoniously with the host. The oral cavity houses …

Periodontal microbiology and microbial etiology of periodontal diseases: historical concepts and contemporary perspectives

GN Belibasakis, D Belstrøm, S Eick… - Periodontology …, 2023 - Wiley Online Library
This narrative review summarizes the collective knowledge on periodontal microbiology,
through a historical timeline that highlights the European contribution in the global field. The …

Microbiome and microbial biofilm profiles of peri‐implantitis: a systematic review

GI Lafaurie, MA Sabogal, DM Castillo… - Journal of …, 2017 - Wiley Online Library
Background: This systematic review assesses microbiologic profiles of peri‐implantitis,
periodontitis, and healthy implants based on studies that evaluated microbial biofilms and …

Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology

G Hajishengallis, RJ Lamont - Molecular oral microbiology, 2012 - Wiley Online Library
Recent advancements in the periodontal research field are consistent with a new model of
pathogenesis according to which periodontitis is initiated by a synergistic and dysbiotic …

Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response

G Hajishengallis - Trends in immunology, 2014 - cell.com
Recent studies have uncovered novel mechanisms underlying the breakdown of periodontal
host–microbe homeostasis, which can precipitate dysbiosis and periodontitis in susceptible …

Periodontitis: a host‐mediated disruption of microbial homeostasis. Unlearning learned concepts

PM Bartold, TE Van Dyke - Periodontology 2000, 2013 - Wiley Online Library
New concepts evolve when existing ones fail to address known factors adequately or are
invalidated by new evidence. For decades periodontitis has been considered to be caused …

Distinct and complex bacterial profiles in human periodontitis and health revealed by 16S pyrosequencing

AL Griffen, CJ Beall, JH Campbell… - The ISME …, 2012 - academic.oup.com
Periodontitis has a polymicrobial etiology within the framework of a complex microbial
ecosystem. With advances in sequencing technologies, comprehensive studies to elucidate …

The oral microbiome diversity and its relation to human diseases

J He, Y Li, Y Cao, J Xue, X Zhou - Folia microbiologica, 2015 - Springer
As one of the most clinically relevant human habitats, the human mouth is colonized by a set
of microorganisms, including bacteria, archaea, fungi, and viruses. Increasing evidence has …

A practical guide to the oral microbiome and its relation to health and disease

K Krishnan, T Chen, BJ Paster - Oral diseases, 2017 - Wiley Online Library
The oral microbiome is incredibly complex with the average adult harboring about 50–100
billion bacteria in the oral cavity, which represent about 200 predominant bacterial species …

Importance of virulence factors for the persistence of oral bacteria in the inflamed gingival crevice and in the pathogenesis of periodontal disease

G Dahlen, A Basic, J Bylund - Journal of clinical medicine, 2019 - mdpi.com
Periodontitis is a chronic inflammation that develops due to a destructive tissue response to
prolonged inflammation and a disturbed homeostasis (dysbiosis) in the interplay between …