Flavonoids: A treasure house of prospective pharmacological potentials

H Hasnat, SA Shompa, MM Islam, S Alam, FT Richi… - Heliyon, 2024 - cell.com
Flavonoids are organic compounds characterized by a range of phenolic structures, which
are abundantly present in various natural sources such as fruits, vegetables, cereals, bark …

Immunomodulatory effect of phytoactive compounds on human health: a narrative review integrated with bioinformatics approach

S Choudhary, S Khan, S Rustagi… - Current Topics in …, 2024 - ingentaconnect.com
Background: Immunomodulation is the modification of immune responses to control disease
progression. While the synthetic immunomodulators have proven efficacy, they are coupled …

Monofloral corn poppy bee-collected pollen—a detailed insight into its phytochemical composition and antioxidant properties

AŽ Kostić, DD Milinčić, B Špirović Trifunović, N Nedić… - Antioxidants, 2023 - mdpi.com
The aim of this study was to compile a detailed phytochemical profile and assess the
antioxidant properties of bee-collected pollen (PBP) obtained from corn poppy (Papaver …

Haploinsufficiency of phosphodiesterase 10A activates PI3K/AKT signaling independent of PTEN to induce an aggressive glioma phenotype

N Nuechterlein, A Shelbourn… - Genes & …, 2024 - genesdev.cshlp.org
Glioblastoma is universally fatal and characterized by frequent chromosomal copy number
alterations harboring oncogenes and tumor suppressors. In this study, we analyzed exome …

[PDF][PDF] Exploring pharmacological potentials of p-coumaric acid: a prospective phytochemical for drug discovery

A Zaman, H Hasnat, Z Al Noman, MM Islam… - Bangladesh …, 2023 - researchgate.net
Abstract p-coumaric acid, commonly referred to as 4-hydroxycinnamic acid, is a phenolic
acid, which has been subjected to much research in recognition of its beneficial properties …

Antibacterial activity of medicinal plants and their role in wound healing

Z Breijyeh, R Karaman - Future Journal of Pharmaceutical Sciences, 2024 - Springer
Background The study of plant-based medications, or phytomedicine, involves a wide
spectrum of biological activities. Due to the existence of secondary metabolites, herbal …

Bracteatinine and isogroenlandicine, two new isoquinoline alkaloids isolated from Corydalis bracteata and their effect on platelet function

AO Whaley, AK Whaley, V Toporkova, E Fock… - Fitoterapia, 2023 - Elsevier
Two previously undescribed isoquinoline alkaloids, bracteatinine (1) and isogroenlandicine
(2), together with four known alkaloids–coptisine (3), dehydrocorydaline (4), palmatine (5) …

Quality markers of Guchang Zhixie pills based on multicomponent qualitative and quantitative analysis combined with network pharmacology and chemometric …

Y Zhang, Q Qu, X Lei, X Zhao, X Zhang, X Wei… - … of Pharmaceutical and …, 2024 - Elsevier
Abstract Traditional Chinese medicine Guchang Zhixie pills (GCZX) is one of the famous
varieties of" Qin medicine" that has been extensively applied to treating irritable bowel …

Natural and Synthetic Phosphodiesterase Inhibitors in 2023: an Update on the Impact on Neurological and Psychiatric Conditions

G Ribaudo, A Gianoncelli - Mini Reviews in Medicinal …, 2024 - ingentaconnect.com
This Perspective provides an updated overview on the involvement of phosphodiesterase
(PDE) isoforms and of the corresponding inhibitors in neurological disorders, including …

[HTML][HTML] The effect of papaverine on tendon healing and adhesion in rats following Achilles tendon repair

E Can, YM Dincel, D Karabulut, S Karabag… - Joint Diseases and …, 2024 - ncbi.nlm.nih.gov
Objectives The study aimed to examine the histopathological and biomechanical effects of
papaverine administered intraperitoneally and locally on Achilles tendon healing in a rat …