Cholesterol plays a significant role in stabilizing lipid or membrane rafts, which are specific
cellular membrane structures. Cholesterol is involved in numerous cellular processes …

Cholesterol synthesis occurs in almost all cells, but mainly in hepatocytes in the liver.
Cholesterol is garnering increasing attention for its central role in various metabolic …

Dysregulation of lipid metabolism is associated with cardiovascular/metabolic diseases,
including atherosclerosis, liver diseases and type 2 diabetes mellitus (T2DM). Several …

Highlights•Dysregulated cholesterol metabolism is seen in cancer cells.•Cholesterol and its
metabolites drive tumorigenesis.•Aberrant cholesterol metabolism opens new therapeutic …

In EGFR-mutant lung cancer, drug-tolerant persister cells (DTPCs) show prolonged survival
when receiving EGFR tyrosine kinase inhibitor (TKI) treatments. They are a likely source of …

Background. Atherosclerosis is considered the most common cause of morbidity and
mortality worldwide. Athermanous plaque formation is pathognomonic of atherosclerosis …

Simple Summary High-density lipoproteins are often described as the 'good'cholesterol in
the bloodstream, as this complex of lipids (fats) and proteins is known to protect many cells …

Cholesterol metabolism is important at the physiological level as well as in several diseases,
with small RNA being an element to consider in terms of its epigenetic control. Thus, the aim …

OBJECTIVE Cardiovascular disease (CVD) accounts for most deaths in patients with type 1
diabetes (T1D); however, the determinants of plaque composition are unknown. miRNAs …

Purpose To explore the association between hysterectomy and cardiovascular disease
(CVD). Methods Observational studies from eight databases and reference lists of relevant …