[HTML][HTML] Single-cell RNA-Seq revealed the gene expression pattern during the in vitro maturation of donkey oocytes

Z Li, X Song, S Yin, J Yan, P Lv, H Shan, K Cui, H Liu… - Genes, 2021 - mdpi.com
Donkeys are an important domesticated animal, providing labor, meat, milk, and medicinal
materials for humans. However, the donkey population is continuously declining and even at …

Sphingosine-1-phosphate (S1P) in ovarian physiology and disease

CG Hernández-Coronado, A Guzmán… - Annales d' …, 2019 - Elsevier
Abstract Sphingosine-1-phoshate (S1P) is a membrane sphingolipid involved in several
physiological processes, including cell proliferation, tissue growth, cell survival and …

[HTML][HTML] Growth factors, gene activation, and cell recruitment: From intraovarian condensed platelet cytokines to de novo oocyte development

ES Sills, SH Wood - Journal of Clinical and Translational Research, 2022 - ncbi.nlm.nih.gov
Background: Interest in decelerating or reversing reproductive aging is unlikely to diminish
in the era of molecular genetics. For the adult human ovary, meeting the challenge of …

Efficient generation of bone morphogenetic protein 15-edited Yorkshire pigs using CRISPR/Cas9

X Shi, T Tang, Q Lin, H Liu, Y Qin, X Liang… - Biology of …, 2020 - academic.oup.com
Abstract Bone morphogenetic protein 15 (BMP15), a member of the transforming growth
factor beta superfamily, plays an essential role in ovarian follicular development in mono …

Molecular characterization of the follicular development of BMP15-edited pigs

Y Jiao, T Jiang, Q Lin, J Guo, C Bei, P Cong… - …, 2023 - rep.bioscientifica.com
In brief The regulatory role of BMP15 on porcine ovarian follicular development still remains
unclear. This study reveals that biallelic editing of BMP15 impairs SMAD signaling and …

Understanding the mechanisms of diminished Ovarian Reserve: insights from genetic variants and Regulatory factors

Q Zhu, H Ma, J Wang, X Liang - Reproductive Sciences, 2024 - Springer
Delaying childbearing age has become a trend in modern times, but it has also led to a
common challenge in clinical reproductive medicine—diminished ovarian reserve (DOR) …

[HTML][HTML] Smad4 feedback enhances BMPR1B transcription in ovine granulosa cells

A Abdurahman, X Du, Y Yao, Y Sulaiman… - International journal of …, 2019 - mdpi.com
BMPR1B is a type 1B receptor of the canonical bone morphogenetic protein (BMP)/Sma-and
mad-related protein (Smad) signaling pathway and is well known as the first major gene …

Maximum‐likelihood approaches reveal signatures of positive selection in BMP15 and GDF9 genes modulating ovarian function in mammalian female fertility

HI Ahmad, G Liu, X Jiang, SG Edallew… - Ecology and …, 2017 - Wiley Online Library
Bone morphogenetic proteins (BMP s) and the growth factors (GDF s) play an important role
in ovarian folliculogenesis and essential regulator of processes of numerous granulosa …

Expression of TGFβ superfamily components and other markers of oocyte quality in oocytes selected by brilliant cresyl blue staining: relevance to early embryonic …

M Ashry, KB Lee, M Mondal, TK Datta… - Molecular …, 2015 - Wiley Online Library
Brilliant cresyl blue (BCB) is a super‐vital stain that has been used to select competent
oocytes in different species. One objective of the present study was to assess the …

Prediction of ovarian aging using ovarian expression of BMP15, GDF9, and C-KIT

MJ Park, JW Ahn, KH Kim, J Bang… - Experimental …, 2020 - journals.sagepub.com
This study investigated ovarian expressions of bone morphogenetic protein 15 (BMP15),
growth differentiation factor 9 (GDF9), and C-KIT according to age in female mice to …