Decoding the spermatogenesis program: new insights from transcriptomic analyses

M Rabbani, X Zheng, GL Manske… - Annual review of …, 2022 - annualreviews.org
Spermatogenesis is a complex differentiation process coordinated spatiotemporally across
and along seminiferous tubules. Cellular heterogeneity has made it challenging to obtain …

Divergence and conservation of the meiotic recombination machinery

M Arter, S Keeney - Nature Reviews Genetics, 2024 - nature.com
Sexually reproducing eukaryotes use recombination between homologous chromosomes to
promote chromosome segregation during meiosis. Meiotic recombination is almost …

[HTML][HTML] Stepwise emergence of the neuronal gene expression program in early animal evolution

SR Najle, X Grau-Bové, A Elek, C Navarrete… - Cell, 2023 - cell.com
The assembly of the neuronal and other major cell type programs occurred early in animal
evolution. We can reconstruct this process by studying non-bilaterians like placozoans …

[HTML][HTML] Molecular quantitative trait loci in reproductive tissues impact male fertility in cattle

XM Mapel, NK Kadri, AS Leonard, Q He… - nature …, 2024 - nature.com
Breeding bulls are well suited to investigate inherited variation in male fertility because they
are genotyped and their reproductive success is monitored through semen analyses and …

Natural antisense transcripts as versatile regulators of gene expression

A Werner, A Kanhere, C Wahlestedt… - Nature Reviews …, 2024 - nature.com
Long non-coding RNAs (lncRNAs) are emerging as a major class of gene products that
have central roles in cell and developmental biology. Natural antisense transcripts (NATs) …

Unraveling patterns of disrupted gene expression across a complex tissue

KE Hunnicutt, JM Good, EL Larson - Evolution, 2022 - academic.oup.com
Whole tissue RNASeq is the standard approach for studying gene expression divergence in
evolutionary biology and provides a snapshot of the comprehensive transcriptome for a …

Sex-biased gene expression at single-cell resolution: cause and consequence of sexual dimorphism

I Darolti, JE Mank - Evolution Letters, 2023 - academic.oup.com
Gene expression differences between males and females are thought to be key for the
evolution of sexual dimorphism, and sex-biased genes are often used to study the molecular …

Functions, Mechanisms, and therapeutic applications of the inositol pyrophosphates 5PP-InsP5 and InsP8 in mammalian cells

J Qi, L Shi, L Zhu, Y Chen, H Zhu, W Cheng… - Journal of …, 2024 - Springer
Water-soluble myo-inositol phosphates have long been characterized as second
messengers. The signaling properties of these compounds are determined by the number …

[HTML][HTML] Comprehensive analyses of 435 goat transcriptomes provides insight into male reproduction

H Xu, S Zhang, Q Duan, M Lou, Y Ling - International Journal of Biological …, 2024 - Elsevier
A systematic analysis of genes related to reproduction is crucial for obtaining a
comprehensive understanding of the molecular mechanisms that underlie male reproductive …

[HTML][HTML] Recent developments in in vitro spermatogenesis and future directions

IK Cho, CA Easley - Reproductive Medicine, 2023 - mdpi.com
Recent developments in stem cell technologies have made significant advancements in the
field of in vitro gametogenesis. In vitro gametogenesis (IVG) is a promising technology …