[HTML][HTML] The bidirectional immune crosstalk in metabolic dysfunction-associated steatotic liver disease

K Sawada, H Chung, S Softic, ME Moreno-Fernandez… - Cell Metabolism, 2023 - cell.com
Metabolic dysfunction-associated steatotic liver disease (MASLD) is an unabated risk factor
for end-stage liver diseases with no available therapies. Dysregulated immune responses …

Mechanistic role of quercetin as inhibitor for adenosine deaminase enzyme in rheumatoid arthritis: systematic review

A Atta, MM Salem, KS El-Said, TM Mohamed - Cellular & Molecular …, 2024 - Springer
Rheumatoid arthritis (RA) is an autoimmune disease involving T and B lymphocytes.
Autoantibodies contribute to joint deterioration and worsening symptoms. Adenosine …

Depletion of soluble cytokines unlocks the immunomodulatory bioactivity of extracellular vesicles

Q Roux, R Boiy, F De Vuyst, M Tkach… - Journal of …, 2023 - Wiley Online Library
Despite an enormous interest in understanding the bioactivity of extracellular vesicles (EV)
in physiology and disease for the development of therapeutic applications, the impact of EV …

Engineering and development of a tissue model for the evaluation of microneedle penetration ability, drug diffusion, photothermal activity, and ultrasound imaging: a …

P Makvandi, M Shabani, N Rabiee… - Advanced …, 2023 - Wiley Online Library
Driven by regulatory authorities and the ever‐growing demands from industry, various
artificial tissue models have been developed. Nevertheless, there is no model to date that is …

Adjuvanted quaternized chitosan composite aluminum nanoparticles-based vaccine formulation promotes immune responses in chickens

J Liu, S Guo, Z Jin, K Zhao - Vaccine, 2023 - Elsevier
Aluminum adjuvant is a typical adjuvant that can promote humoral immune response, but it
lacks the ability to effectively induce cellular immune response. The water-soluble N-2 …

[HTML][HTML] Contextualizing protein representations using deep learning on protein networks and single-cell data

MM Li, Y Huang, M Sumathipala, MQ Liang… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Understanding protein function and developing molecular therapies require deciphering the
cell types in which proteins act as well as the interactions between proteins. However …

Role of nanomaterials in screenprinted electrochemical biosensors for detection of COVID-19 and for post-covid syndromes

D Sundeep, EK Varadharaj, K Umadevi… - ECS Advances, 2023 - iopscience.iop.org
Covid-19 still remains as global pandemic surging with different variants like alpha, beta,
gamma, delta and most omicronin various countries resulted into SARS-CoV-2. An …

A biomimetic, silaffin R5-based antigen delivery platform

D Reichinger, M Reithofer, M Hohagen, M Drinic… - Pharmaceutics, 2022 - mdpi.com
Nature offers a wide range of evolutionary optimized materials that combine unique
properties with intrinsic biocompatibility and that can be exploited as biomimetic materials …

An interleukin 6‐based genetic risk score strengthened with interleukin 10 polymorphisms associated with long‐term kidney allograft outcomes

SK Eskandari, M Gaya da Costa, B Faria… - American Journal of …, 2022 - Wiley Online Library
Of all kidney transplants, half are still lost in the first decade after transplantation. Here, using
genetics, we probed whether interleukin 6 (IL‐6) could be a target in kidney transplantation …

A human 3D immune competent full-thickness skin model mimicking dermal dendritic cell activation

JM Hölken, K Friedrich, M Merkel, N Blasius… - Frontiers in …, 2023 - frontiersin.org
We have integrated dermal dendritic cell surrogates originally generated from the cell line
THP-1 as central mediators of the immune reaction in a human full-thickness skin model …