Network pharmacology, a promising approach to reveal the pharmacology mechanism of Chinese medicine formula

L Zhao, H Zhang, N Li, J Chen, H Xu, Y Wang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Network pharmacology is a new discipline based on
systems biology theory, biological system network analysis, and multi-target drug molecule …

Network pharmacology approach for medicinal plants: review and assessment

F Noor, M Tahir ul Qamar, UA Ashfaq, A Albutti… - Pharmaceuticals, 2022 - mdpi.com
Natural products have played a critical role in medicine due to their ability to bind and
modulate cellular targets involved in disease. Medicinal plants hold a variety of bioactive …

Network pharmacology prediction and molecular docking-based strategy to discover the potential pharmacological mechanism of Huai Hua San against ulcerative …

J Liu, J Liu, X Tong, W Peng, S Wei, T Sun… - Drug Design …, 2021 - Taylor & Francis
Background Huai Hua San (HHS), a famous Traditional Chinese Medicine (TCM) formula,
has been widely applied in treating ulcerative colitis (UC). However, the interaction of …

[HTML][HTML] Potential compound from herbal food of Rhizoma Polygonati for treatment of COVID-19 analyzed by network pharmacology: Viral and cancer signaling …

C Mu, Y Sheng, Q Wang, A Amin, X Li, Y Xie - Journal of Functional Foods, 2021 - Elsevier
Abstract Rhizoma Polygonati (huangjing in Chinese, 黄精) is a medicine food homology
herb used as a component of traditional Chinese medicine treating COVID-19 in the current …

Network pharmacology provides a systematic approach to understanding the treatment of ischemic heart diseases with traditional Chinese medicine

HY Yang, ML Liu, P Luo, XS Yao, H Zhou - Phytomedicine, 2022 - Elsevier
Background The field of network pharmacology showed significant development. The
concept of network pharmacology has many similarities to the philosophy of traditional …

Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K …

Y Wang, F Chu, J Lin, Y Li, N Johnson, J Zhang… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Dendrobium chrysotoxum Lindl, a well-known
traditional Chinese medicinal herb used in the treatment of gastric disease, is distinguished …

Progress and prospects of research ideas and methods in the network pharmacology of traditional Chinese medicine

Z Yuan, Y Pan, T Leng, Y Chu… - … of Pharmacy & …, 2022 - journals.library.ualberta.ca
In recent years, the emerging network pharmacology has been extensively applied to the
field of traditional Chinese medicine and has made great contributions to the modernization …

A network pharmacology-based investigation of brugine reveals its multi-target molecular mechanism against Breast Cancer

H Qayoom, M Alkhanani, A Almilaibary, SA Alsagaby… - Medical Oncology, 2023 - Springer
Breast cancer represents the leading cause of mortality among women worldwide. Since the
complexity of breast cancer as a disease resides in its heterogeneity as it consists of several …

Integrating hippocampal metabolomics and network pharmacology deciphers the antidepressant mechanisms of Xiaoyaosan

X Liu, F Wei, H Liu, S Zhao, G Du, X Qin - Journal of Ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Xiaoyaosan (XYS), a classic description, has a history of
thousands of years for treating depression through invigorating the liver and strengthening …

Integrated network pharmacology and cellular assay for the investigation of an anti-obesity effect of 6-shogaol

W Jiao, S Mi, Y Sang, Q Jin, B Chitrakar, X Wang… - Food Chemistry, 2022 - Elsevier
This study explored the anti-obesity effect of 6-shogaol and the underlying mechanisms by
using Network pharmacology for the prediction and verification of molecular targets and …