Molecular mechanisms of secretory autophagy and its potential role in diseases

Q Li, G Peng, H Liu, L Wang, R Lu, L Li - Life Sciences, 2024 - Elsevier
Autophagy is a cellular degradation system that recycles or degrades damaged organelles,
viral particles, and aggregated proteins through the lysosomal pathway. Autophagy plays an …

Emerging roles of exosomes in oral diseases progression

J Wang, J Jing, C Zhou, Y Fan - International Journal of Oral Science, 2024 - nature.com
Oral diseases, such as periodontitis, salivary gland diseases, and oral cancers, significantly
challenge health conditions due to their detrimental effects on patient's digestive functions …

Anticancer potential of thiocolchicoside and lauric acid loaded chitosan nanogel against oral cancer cell lines: a comprehensive study

A Mustafa, MA Indiran, K Ramalingam, E Perumal… - Scientific Reports, 2024 - nature.com
The present study explored the anticancer activity of a Chitosan-based nanogel
incorporating thiocolchicoside and lauric acid (CTL) against oral cancer cell lines (KB-1) …

The role of CXCL2-mediated crosstalk between tumor cells and macrophages in Fusobacterium nucleatum-promoted oral squamous cell carcinoma progression

F Nie, J Zhang, H Tian, J Zhao, P Gong, H Wang… - Cell Death & …, 2024 - nature.com
Dysbiosis of the oral microbiota is related to chronic inflammation and carcinogenesis.
Fusobacterium nucleatum (Fn), a significant component of the oral microbiota, can perturb …

WNT7A promotes tumorigenesis of head and neck squamous cell carcinoma via activating FZD7/JAK1/STAT3 signaling

Q Huang, Y Xiao, T Lan, Y Lu, L Huang… - International Journal of …, 2024 - nature.com
Wnt signaling are critical pathway involved in organ development, tumorigenesis, and
cancer progression. WNT7A, a member of the Wnt family, remains poorly understood in …

Strategic approaches in oral squamous cell carcinoma diagnostics using liquid biopsy

DF Kinane, J Gabert, G Xynopoulos… - Periodontology …, 2024 - Wiley Online Library
Liquid biopsy is a noninvasive diagnostic technique used for monitoring cancer utilizing
specific genetic biomarkers present in bodily fluids, such as blood, saliva, or urine. These …

Advancing oral cancer diagnosis in Brazil: Integrating artificial intelligence with teledentistry for enhanced patient outcomes

LA da Mota Santana, LG Floresta… - Oral …, 2024 - pubmed.ncbi.nlm.nih.gov
Advancing oral cancer diagnosis in Brazil: Integrating artificial intelligence with teledentistry for
enhanced patient outcomes Advancing oral cancer diagnosis in Brazil: Integrating artificial …

Oral health and multimorbidity: Is diet the chicken or the egg?

TA Marshall, R Touger-Decker - Proceedings of the Nutrition Society, 2024 - cambridge.org
Oral health is a critical component of overall health and well-being, not just the absence of
disease. The objective of this review paper is to describe relationships among diet, nutrition …

Cascade Nanoreactor Employs Mitochondrial‐Directed Chemodynamic and δ‐ALA‐Mediated Photodynamic Synergy for Deep‐Seated Oral Cancer Therapy

Q Yin, J Zhang, H Zhang, J Gao, L Weng… - Advanced …, 2024 - Wiley Online Library
The management of oral squamous cell carcinoma (OSCC) poses significant challenges,
leading to organ impairment and ineffective treatment of deep‐seated tumors, adversely …

The anticancer activity of bile acids in drug discovery and development

W Li, L Zou, S Huang, H Miao, K Liu, Y Geng… - Frontiers in …, 2024 - frontiersin.org
Bile acids (BAs) constitute essential components of cholesterol metabolites that are
synthesized in the liver, stored in the gallbladder, and excreted into the intestine through the …