Polygenic predictions of occupational status GWAS elucidate genetic and environmental interplay for intergenerational status transmission, careers, and health

ET Akimova, T Wolfram, X Ding, FC Tropf, MC Mills - bioRxiv, 2023 - biorxiv.org
Socioeconomic status (SES) stratifies society and impacts our health and life course. We
conducted the first sociologically informed GWAS on occupational status and prestige …

[HTML][HTML] Genetic predisposition for negative affect predicts mental health burden during the COVID-19 pandemic

AM Schowe, M Godara, D Czamara, M Adli… - European Archives of …, 2024 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic was accompanied by an
increase in mental health challenges including depression, stress, loneliness, and anxiety …

Educational influences on late-life health: Genetic propensity and attained education

M Ericsson, B Finch, IK Karlsson, M Gatz… - The Journals of …, 2024 - academic.oup.com
Objectives The educational gradient in late-life health is well established. Despite this, there
are still ambiguities concerning the role of underlying confounding by genetic influences and …

[HTML][HTML] Psychological resilience and neurodegenerative risk: A connectomics‐transcriptomics investigation in healthy adolescent and middle‐aged females

R Petrican, A Fornito, N Jones - NeuroImage, 2022 - Elsevier
Adverse life events can inflict substantial long-term damage, which, paradoxically, has been
posited to stem from initially adaptative responses to the challenges encountered in one's …

Confronting ethical and social issues related to the genetics of musicality

RL Gordon, DO Martschenko, S Nayak… - Annals of the New …, 2023 - Wiley Online Library
New interdisciplinary research into genetic influences on musicality raises a number of
ethical and social issues for future avenues of research and public engagement. The …

[HTML][HTML] Notes from Beethoven's genome

LW Wesseldijk, TL Henechowicz, DJ Baker, G Bignardi… - Current Biology, 2024 - cell.com
Rapid advances over the last decade in DNA sequencing and statistical genetics enable us
to investigate the genomic makeup of individuals throughout history. In a recent notable …

Developmental perspectives on the origins of psychotic disorders: The need for a transdiagnostic approach

EF Walker, K Aberizk, E Yuan, Z Bilgrami… - Development and …, 2024 - cambridge.org
Research on serious mental disorders, particularly psychosis, has revealed highly variable
symptom profiles and developmental trajectories prior to illness-onset. As Dante Cicchetti …

[HTML][HTML] Using a polygenic score in a family design to understand genetic influences on musicality

LW Wesseldijk, A Abdellaoui, RL Gordon, F Ullén… - Scientific reports, 2022 - nature.com
To further our understanding of the genetics of musicality, we explored associations
between a polygenic score for self-reported beat synchronization ability (PGSrhythm) and …

Socioeconomic status and severe mental disorders: a bidirectional multivariable Mendelian randomisation study

Á Andreu-Bernabeu, J González-Peñas… - BMJ Ment …, 2023 - mentalhealth.bmj.com
Background Despite the evidence supporting the relationship between socioeconomic
status (SES) and severe mental disorders (SMD), the directionality of the associations …

[HTML][HTML] Schooling substantially improves intelligence, but neither lessens nor widens the impacts of socioeconomics and genetics

N Judd, B Sauce, T Klingberg - npj Science of Learning, 2022 - nature.com
Abstract Schooling, socioeconomic status (SES), and genetics all impact intelligence.
However, it is unclear to what extent their contributions are unique and if they interact. Here …