Cholangiocarcinoma 2020: the next horizon in mechanisms and management

JM Banales, JJG Marin, A Lamarca… - Nature reviews …, 2020 - nature.com
Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally …

AASLD practice guidance on primary sclerosing cholangitis and cholangiocarcinoma

CL Bowlus, L Arrivé, A Bergquist, M Deneau… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …

[HTML][HTML] Tumor microenvironment and its implications for antitumor immunity in cholangiocarcinoma: Future perspectives for novel therapies

H Cao, T Huang, M Dai, X Kong, H Liu… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
The incidence of cholangiocarcinoma (CCA) has been increasing over the past few years.
Although there are surgery, chemotherapy and other conventional treatment methods, the …

[HTML][HTML] Artificial intelligence in liver cancers: Decoding the impact of machine learning models in clinical diagnosis of primary liver cancers and liver cancer …

A Bakrania, N Joshi, X Zhao, G Zheng, M Bhat - Pharmacological research, 2023 - Elsevier
Liver cancers are the fourth leading cause of cancer-related mortality worldwide. In the past
decade, breakthroughs in the field of artificial intelligence (AI) have inspired development of …

Identification of patients with malignant biliary strictures using a cholangioscopy-based deep learning artificial intelligence (with video)

NB Marya, PD Powers, BT Petersen, R Law… - Gastrointestinal …, 2023 - Elsevier
Background and Aims Accurately diagnosing malignant biliary strictures (MBSs) as benign
or malignant remains challenging. It has been suggested that direct visualization and …

Molecular profiling and treatment pattern differences between intrahepatic and extrahepatic cholangiocarcinoma

K Spencer, L Pappas, I Baiev, J Maurer… - JNCI: Journal of the …, 2023 - academic.oup.com
Background Treatment patterns for intrahepatic cholangiocarcinoma (ICC) and extrahepatic
cholangiocarcinoma (ECC) differ, but limited studies exist comparing them. This study …

[HTML][HTML] Liver transplantation in the management of cholangiocarcinoma: Evolution and contemporary advances

A Borakati, F Froghi, RH Bhogal… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Cholangiocarcinoma (CCA) is an aggressive malignancy arising from the biliary epithelium.
It may occur at any location along the biliary tree with the perihilar area being the most …

Next-generation biomarkers for cholangiocarcinoma

PM Rodrigues, A Vogel, M Arrese, DC Balderramo… - Cancers, 2021 - mdpi.com
Simple Summary Early and non-invasive diagnosis of cholangiocarcinoma (CCA) is still
challenging, thus largely contributing to the increased mortality rates observed worldwide …

The state of immunotherapy in hepatobiliary cancers

FZ Ilyas, JD Beane, TM Pawlik - Cells, 2021 - mdpi.com
Hepatobiliary cancers, including hepatocellular carcinoma (HCC), cholangiocarcinoma
(CCA), and gallbladder carcinoma (GBC), are lethal cancers with limited therapeutic options …

[HTML][HTML] Mesenchymal stem cell‑derived exosomes loaded with 5‑Fu against cholangiocarcinoma in vitro

M Chen, Y Li, N Ma, J Zang - Molecular Medicine …, 2022 - spandidos-publications.com
Cholangiocarcinoma (CCA) is an intractable malignant tumour with a high degree of
malignancy that is asymptomatic in the early stages. Exosomes have been shown in …