Efficacy of SARS-CoV-2 vaccines and the dose–response relationship with three major antibodies: a systematic review and meta-analysis of randomised controlled …

ZR Yang, YW Jiang, FX Li, D Liu, TF Lin… - The Lancet …, 2023 - thelancet.com
Background The efficacy of SARS-CoV-2 vaccines in preventing severe COVID-19 illness
and death is uncertain due to the rarity of data in individual trials. How well the antibody …

The role of vaccines in the COVID-19 pandemic: what have we learned?

F Krammer - Seminars in Immunopathology, 2024 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged late in 2019 and
caused the coronavirus disease 2019 (COVID-19) pandemic that has so far claimed …

An overview of the vaccine platforms to combat COVID-19 with a focus on the subunit vaccines

F Bayani, NS Hashkavaei, S Arjmand, S Rezaei… - Progress in Biophysics …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emerging virus that
has caused the recent coronavirus disease (COVID-19) global pandemic. The current …

A phase 3, randomised, double-blind, placebo-controlled clinical trial evaluation of the efficacy and safety of a SARS-CoV-2 recombinant spike RBD protein vaccine in …

F Hernández-Bernal, MC Ricardo-Cobas… - The Lancet Regional …, 2023 - thelancet.com
Background The pandemic of COVID-19 raised the urgent need for safe and efficacious
vaccines against SARS-CoV-2. We evaluated the efficacy and safety of a new SARS-CoV-2 …

Interim results from a phase I randomized, placebo-controlled trial of novel SARS-CoV-2 beta variant receptor-binding domain recombinant protein and mRNA …

TM Nolan, G Deliyannis, M Griffith, S Braat, LF Allen… - …, 2023 - thelancet.com
Background SARS-CoV-2 booster vaccination should ideally enhance protection against
variants and minimise immune imprinting. This Phase I trial evaluated two vaccines targeting …

Application of traditional vaccine development strategies to SARS-CoV-2

HM Rando, R Lordan, AJ Lee, A Naik, N Wellhausen… - Msystems, 2023 - Am Soc Microbiol
Over the past 150 years, vaccines have revolutionized the relationship between people and
disease. During the COVID-19 pandemic, technologies such as mRNA vaccines have …

Safety of COVID-19 vaccines in patients with autoimmune diseases, in patients with cardiac issues, and in the healthy population

L Frasca, G Ocone, R Palazzo - Pathogens, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) has been a challenge for the whole world since
the beginning of 2020, and COVID-19 vaccines were considered crucial for disease …

Efficacy and safety of a protein-based SARS-CoV-2 vaccine: a randomized clinical trial

E Mostafavi, S Eybpoosh, M Karamouzian… - JAMA Network …, 2023 - jamanetwork.com
Importance The protein-based SARS-CoV-2 vaccines FINLAY-FR-2 (Soberana 02) and
FINLAY-FR-1A (Soberana Plus) showed good safety and immunogenicity in phase 1 and 2 …

Three doses of a recombinant conjugated SARS-CoV-2 vaccine early after allogeneic hematopoietic stem cell transplantation: predicting indicators of a high serologic …

M Barkhordar, B Chahardouli, A Biglari… - Frontiers in …, 2023 - frontiersin.org
Background Allogeneic hematopoietic stem cell transplant (allo-HSCT) recipients must be
vaccinated against SARS-CoV-2 as quickly as possible after transplantation. The difficulty in …

Homologous versus Heterologous prime-boost COVID-19 Vaccination in autologous hematopoietic stem cell transplantation recipients: a blinded randomized …

L Sharifi Aliabadi, M Karami, M Barkhordar… - Frontiers in …, 2023 - frontiersin.org
Background/Purpose Optimizing vaccine efficacy is of particular concern in patients
undergoing hematopoietic stem cell transplantation (HSCT), which mainly have an …