Ironing out the role of ferroptosis in immunity

HN Bell, BR Stockwell, W Zou - Immunity, 2024 - cell.com
Ferroptosis is a type of regulated cell death that drives the pathophysiology of many
diseases. Oxidative stress is detectable in many types of regulated cell death, but only …

Therapeutic exploitation of ferroptosis

M Walravens, I Koeken… - Biochemical Society …, 2024 - portlandpress.com
Pathological breakdown of membrane lipids through excessive lipid peroxidation (LPO) was
first described in the mid-20th century and is now recognized as a form of regulated cell …

[HTML][HTML] Effects of Natural Products on Enzymes Involved in Ferroptosis: Regulation and Implications

HL Zuo, HY Huang, YCD Lin, KM Liu, TS Lin, YB Wang… - Molecules, 2023 - mdpi.com
Ferroptosis is a form of regulated cell death that is characterized by the accumulation of iron-
dependent lipid peroxides. The regulation of ferroptosis involves both non-enzymatic …

Bletilla striata polysaccharides protect against ARDS by modulating the NLRP3/caspase1/GSDMD and HMGB1/TLR4 signaling pathways to improve pulmonary …

Q Wu, M Zhou, Y Chen, B Zhu, F Zhou, X Ye… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Bletilla striata polysaccharides (BSP) extracted from the B.
striata tuber, have been demonstrated to possess anti-inflammatory properties. However …

[HTML][HTML] A deep insight into ferroptosis in lung disease: facts and perspectives

F Zhang, Y Xiang, Q Ma, E Guo, X Zeng - Frontiers in Oncology, 2024 - frontiersin.org
In the last decade, ferroptosis has received much attention from the scientific research
community. It differs from other modes of cell death at the morphological, biochemical, and …

Understanding COVID-19 outcome: Exploring the prognostic value of soluble biomarkers indicative of endothelial impairment

V Mariappan, D Adla, S Jangili, P Ranganadin… - Cytokine, 2024 - Elsevier
Host proteins released by the activated endothelial cells during SARS-CoV-2 infection are
implicated to be involved in coagulation and endothelial dysfunction. However, the …

[HTML][HTML] Circulating and Urinary Concentrations of Malondialdehyde in Aging Humans in Health and Disease: Review and Discussion

D Tsikas, SA Tsikas, M Mikuteit, S Ückert - Biomedicines, 2023 - mdpi.com
(1) Background: Malondialdehyde (MDA) is a major and stable product of oxidative stress.
MDA circulates in the blood and is excreted in the urine in its free and conjugated forms …

Alterations in microbiota of patients with COVID‐19: implications for therapeutic interventions

Y Qiu, C Mo, L Chen, W Ye, G Chen, T Zhu - MedComm, 2024 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) recently caused a global
pandemic, resulting in more than 702 million people being infected and over 6.9 million …

Visual Analysis on Ferroptosis and its Cross-Talk to Coronavirus Disease 2019 (Covid-19)

J Zhou, X Zhang, M Yang, X Liu, J Guo, J Li… - Available at SSRN … - papers.ssrn.com
Background. Ferroptosis is a new type of programmed cell death. Although ferroptosis has
been studied in various aspects, there has been no visual analysis of ferroptosis in …