[HTML][HTML] The role of IL-6-174 G/C polymorphism and intraocular IL-6 levels in the pathogenesis of ocular diseases: a systematic review and meta-analysis

ZS Ulhaq, GV Soraya, Budu, LR Wulandari - Scientific reports, 2020 - nature.com
Abstract Interleukin-6 (IL-6) is one of the key regulators behind the inflammatory and
pathological process associated with ophthalmic diseases. The role of IL-6-174 G/C …

[HTML][HTML] Role of tear film biomarkers in the diagnosis and management of dry eye disease

PY Fong, KC Shih, PY Lam, TCY Chan… - Taiwan journal of …, 2019 - journals.lww.com
In recent years, there has been increasing scientific interest in the use of tear film biomarkers
in the diagnosis and management of dry eye disease (DED), owing to their potential …

[HTML][HTML] Interferons and dry eye in Sjögren's syndrome

Y Ogawa, E Shimizu, K Tsubota - International journal of molecular …, 2018 - mdpi.com
Various cytokines, including interferon (IFN)-γ and IL-17, are augmented, and autoreactive T
cells and B cells are activated in the immune pathogenesis of Sjögren's syndrome (SS). In …

Intense pulsed light (IPL) therapy for the treatment of meibomian gland dysfunction

S Cote, AC Zhang, V Ahmadzai… - Cochrane Database …, 1996 - cochranelibrary.com
Background Meibomian gland dysfunction (MGD) is the major cause of evaporative dry eye
disease, which is the more prevalent form of dry eye disease. Intense pulsed light (IPL) …

[HTML][HTML] Modulating contact lens discomfort with anti-inflammatory approaches: a randomized controlled trial

LE Downie, A Gad, CY Wong, JHV Gray… - … & visual science, 2018 - iovs.arvojournals.org
Purpose: To assess the efficacy of anti-inflammatory approaches, comprising a topical
corticosteroid and omega-3 supplements, for modulating the inflammatory overlay …

Association of tear cytokine concentrations with symptoms and signs of dry eye disease: baseline data from the Dry Eye Assessment and Management (DREAM) study

NS Roy, Y Wei, GS Ying, MG Maguire… - Current Eye …, 2023 - Taylor & Francis
Purpose To describe tear concentrations of IL-1β, Il-6, IL-8, IL-10, IL-17A, IFNγ and TNFα in
tears, collected by microcapillaries, and their correlation with symptoms and signs in …

Tear film inflammatory cytokine upregulation in contact lens discomfort

A Gad, AJ Vingrys, CY Wong, DC Jackson, LE Downie - The ocular surface, 2019 - Elsevier
Purpose To investigate the ocular inflammatory response, using clinical and immunological
techniques, in people experiencing contact lens (CL) discomfort. Methods This study …

Tear film evaluation and management in soft contact lens wear: a systematic approach

LE Downie, JP Craig - Clinical and Experimental Optometry, 2017 - Taylor & Francis
The human tear film is a highly ordered structure consisting of a thin layer of lipid on the
surface and a thicker aqueous‐mucin phase, which increases in mucin concentration toward …

A review of diagnostic tests for qualitative and quantitative tear film deficiency in dogs

H Iwashita, L Sebbag, BC Leonard… - Veterinary …, 2023 - Wiley Online Library
Dry eye disease (DED) is a complex multifactorial condition caused by loss of ocular surface
homeostasis from quantitative and/or qualitative tear film deficiency. Schirmer tear test (STT) …

[HTML][HTML] Correlation between the inflammatory marker HLA-DR and signs and symptoms in moderate to severe dry eye disease

F Brignole-Baudouin, L Riancho… - … & visual science, 2017 - tvst.arvojournals.org
Purpose: To investigate correlations of the inflammatory HLA-DR marker with clinical signs
and symptoms commonly used to assess dry eye disease (DED) severity. Methods: Baseline …