In the last decade, Chimeric Antigen Receptor (CAR)-T cell therapy has emerged as a
promising immunotherapeutic approach to fight cancers. This approach consists of …

Nucleic acid therapy can achieve lasting and even curative effects through gene
augmentation, gene suppression, and genome editing. However, it is difficult for naked …

The ionizable-lipid component of RNA-containing nanoparticles controls the pH-dependent
behavior necessary for an efficient delivery of the cargo—the so-called endosomal escape …

Graphene is a highly versatile two-dimensional carbon-based material employed in several
research areas having progressive characteristics comprising properties like high surface …

In recent years, nanoparticles derived from cellular membranes have been increasingly
explored for the prevention and treatment of human disease. With their flexible design and …

Skin wounds are a common condition causing economic burden and they represent an
urgent clinical need, especially chronic wounds. Numerous studies have been conducted on …

Breast cancer incidence and mortality rates have increased exponentially during the last
decade, particularly among female patients. Current therapies, including surgery and …

Monoclonal antibodies (mAbs) have been used in the development of immunotherapies that
target a variety of diseases, such as cancer, autoimmune diseases, and even viral infections; …

Exosomes are the small extracellular vesicles secreted by cells for intercellular
communication. Exosomes are rich in therapeutic cargos such as microRNA (miRNA), long …

In the 20 years since the first report of a proteolysis targeting chimeric (PROTAC) molecule,
targeted protein degradation (TPD) technologies have attempted to revolutionize the fields …