Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

Pain is an unpleasant sensory and emotional experience associated with actual or potential
tissue damage. Chronic pain, with a prevalence of 20–30% is the major cause of human …

The specific neural systems underlying the subjective feeling of fear are debated in affective
neuroscience. Here, we combine functional MRI with machine learning to identify and …

Anxiety and depressive disorders are among the most common psychiatric illnesses; they
are highly comorbid with each other, and together they are considered to belong to the …

Psychiatric disorders share neurobiology and frequently co-occur. This neurobiological and
clinical overlap highlights opportunities for transdiagnostic treatments. In this study, we used …

Eating disorders (anorexia nervosa, bulimia nervosa and binge-eating disorder) are a
heterogeneous class of complex illnesses marked by weight and appetite dysregulation …

Considerable work has advanced understanding of the nature, causes, management, and
prevention of anxiety disorders in children and adolescents over the past 30 years. Prior to …

The gabapentinoids, gabapentin, and pregabalin, target the α2δ subunits of voltage-gated
calcium channels. Initially licensed for pain and seizures, they have become widely …

In light of the National Institute of Mental Health (NIMH)'s Research Domain Criteria (RDoC),
the advent of functional neuroimaging, novel technologies and methods provide new …

The amygdala processes valenced stimuli, influences emotion, and exhibits aberrant activity
across anxiety disorders, depression, and PTSD. Interventions modulating amygdala activity …