Leptospirosis is a widespread and potentially fatal zoonosis that is endemic in many tropical
regions and causes large epidemics after heavy rainfall and flooding. Infection results from …

Leptospirosis is a widespread bacterial zoonosis with highest burden in low-income
populations living in tropical and subtropical regions, both in urban and in rural …

Leptospira is a highly heterogeneous bacterial genus that can be divided into three
evolutionary lineages and> 300 serovars. The causative agents of leptospirosis are …

Leptospirosis is a zoonotic disease caused by the pathogenic helical spirochetes,
Leptospira. Symptoms include sudden-onset fever, severe headaches, muscle pain, nausea …

Background One of the key barriers preventing rapid diagnosis of leptospirosis is the lack of
available sensitive point-of-care testing. This study aimed to develop and validate a …

Background The Pacific Islands have environmental conditions highly favourable for
transmission of leptospirosis, a neglected zoonosis with highest incidence in the tropics, and …

Leptospirosis is an important zoonotic disease, causing about 60,000 deaths annually. In
this review, we have described in detail the immunopathogenesis of leptospirosis, the …

Molecular diagnostics have an established role for the diagnosis of leptospirosis and
provide an actionable diagnosis in the acute setting. The use of real-time reverse …

Background The case-fatality rate of severe leptospirosis can exceed 50%. While prompt
supportive care can improve survival, predicting those at risk of developing severe disease …

Leptospirosis is one of the most widespread zoonoses in the Transcarpathian region, with
an average lethality of 12.5%. To determine the predictors of lethality, a retrospective study …