Schizophrenia is a severe mental disorder that affects approximately one percent of the
general population. The pathogenesis of schizophrenia is influenced by many risk factors …

The WAVE regulatory complex (WRC), composed of five components—Cyfip1/Sra1,
WAVE/Scar, Abi, Nap1/Nckap1, and Brk1/HSPC300—is essential for proper actin …

Background Compelling evidence suggested the role of copy number variations (CNVs) in
schizophrenia susceptibility. Most of the evidence was from studies in populations with …

Adequate micronutrient intake, including manganese (Mn), is important for fetal
development. Both Mn deficiencies and excess exposures are associated with later-life …

Failure in establishment and maintenance of epithelial cell polarity contributes to
tumorigenesis. Loss of expression and function of cell polarity proteins is directly related to …

Schizophrenia is a severe neuropsychiatric disorder affecting 1% of the world population.
Disturbances in neuronal development and synaptic connections are important factors in the …

Schizophrenia (SCZ) is a complex neuropsychiatric disorder with high heritability. Abnormal
gene methylation was found to play a key role in the development of SCZ, suggesting that …

Pruning in neurons has been suggested to be strongly involved in Schizophrenia's (SKZ)
etiopathogenesis in recent biological, imaging, and genetic studies. We investigated the …

The chromosome 1q21. 1 duplication syndrome (OMIM# 612475) is characterized by head
anomalies, mild facial dysmorphisms, and cognitive problems, including autistic features …

5′ AMP-activated protein kinase (AMPK) is considered the master metabolic regulator in all
eukaryotes, as it maintains cellular energy homeostasis in a variety of tissues, including the …