Effects of combined exposures of fluoranthene and polyethylene or polyhydroxybutyrate microplastics on oxidative stress biomarkers in the blue mussel (Mytilus edulis …

G Magara, FR Khan, M Pinti, K Syberg… - Journal of Toxicology …, 2019 - Taylor & Francis
ABSTRACT A growing interest in developing and commercialization of new eco-friendly
plastic polymers is occurring attributed to the impact of marine plastics debris and …

Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2

C Syng-Ai, AL Kumari, A Khar - Molecular cancer therapeutics, 2004 - AACR
Curcumin, a well-known dietary pigment derived from Curcuma longa, inhibited growth of
several types of malignant cells both in vivo and in vitro. However, its mechanism of action …

5-Hydroxymethylfurfural: assessment of mutagenicity, DNA-damaging potential and reactivity towards cellular glutathione

C Janzowski, V Glaab, E Samimi, J Schlatter… - Food and chemical …, 2000 - Elsevier
5-(Hydroxymethyl)-2-furfural (HMF), a common product of the Maillard reaction, occurs in
many foods in high concentrations, sometimes exceeding 1 g/kg (in certain dried fruits and …

A comprehensive review on carbon dots and graphene quantum dots based fluorescent sensor for biothiols

ZG Khan, PO Patil - Microchemical Journal, 2020 - Elsevier
Fluorescent carbon-based nanomaterials such as carbon dots (CDs) and graphene
quantum dots (GQDs) owing to their high aqueous solubility, stable photoluminescence and …

In vitro and in vivo hepatoprotective effects of the aqueous extract from Taraxacum officinale (dandelion) root against alcohol-induced oxidative stress

Y You, S Yoo, HG Yoon, J Park, YH Lee, S Kim… - Food and chemical …, 2010 - Elsevier
The protective effects of Taraxacum officinale (dandelion) root against alcoholic liver
damage were investigated in HepG2/2E1 cells and ICR mice. When an increase in the …

[HTML][HTML] Overexpression of a novel anionic glutathione transferase in multidrug-resistant human breast cancer cells.

G Batist, A Tulpule, BK Sinha, AG Katki… - Journal of Biological …, 1986 - Elsevier
Adriamycin-resistant (AdrR) human breast cancer cells have been selected which exhibit
cross-resistance to a wide range of anti-cancer drugs. This multidrug-resistant phenotype is …

Oxidative stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells

F Wang, F Gao, M Lan, H Yuan, Y Huang, J Liu - Toxicology in vitro, 2009 - Elsevier
In order to elucidate the nanoparticle-induced cytotoxicity and its mechanism, the effects of
20 and 50nm silica nanoparticles on cultured human embryonic kidney (HEK293) cells were …

Preclinical antitumor activity of cabazitaxel, a semisynthetic taxane active in taxane-resistant tumors

P Vrignaud, D Sémiond, P Lejeune, H Bouchard… - Clinical Cancer …, 2013 - AACR
Purpose: Taxanes are important chemotherapeutic agents with proven efficacy in human
cancers, but their use is limited by resistance development. We report here the preclinical …

[HTML][HTML] Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells

S Pei, M Minhajuddin, KP Callahan, M Balys… - Journal of Biological …, 2013 - ASBMB
The development of strategies to eradicate primary human acute myelogenous leukemia
(AML) cells is a major challenge to the leukemia research field. In particular, primitive …

Plasma glutathione and glutathione disulfide in the rat: regulation and response to oxidative stress.

JD Adams, BH Lauterburg, JR Mitchell - Journal of Pharmacology and …, 1983 - ASPET
Plasma GSH and GSSG concentrations were examined after the administration of
compounds that deplete intracellular GSH either by adduct formation or by production of …