The host immune response against severe acute respiratory syndrome coronavirus 2
includes the induction of a group of natural antiviral cytokines called interferons (IFNs) …

Host genetic factors significantly influence susceptibility to SARS-CoV-2 infection and
COVID-19 severity. Among these genetic factors are single-nucleotide variants (SNVs) …

The COVID-19 pandemic remains a significant public health concern despite the new
vaccines and therapeutics. The clinical course of acute SARS-CoV-2 infection is highly …

Recent advances in adaptive immune receptor repertoire sequencing have provided
abundant B cell receptor (BCR) sequences under various conditions, including vaccination …

Background Research on whether gastrointestinal symptoms correlate with the severity of
Coronavirus Disease 2019 (COVID-19) has been inconclusive. This study aimed to clarify …

People hospitalized with COVID-19 often exhibit altered hematological traits associated with
disease prognosis (eg, lower lymphocyte and platelet counts). We investigated whether inter …

The mechanisms explaining the variability in COVID-19 clinical manifestations (mild,
moderate, and severe) are not fully understood. To identify key gene expression markers …

The lung-resident immune mechanisms driving resolution of SARS-CoV-2 infection in
humans remain elusive. Using mice co-engrafted with a genetically matched human …

Currently, since there are still some inconsistencies in the severity data types of COVID‐19
among different hospitals or sources [8], we aimed to establish a consistent severity score for …

Objective Extracting immunological and clinical heterogeneity across autoimmune
rheumatic diseases (AIRDs) is essential towards personalised medicine. Methods We …