Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Aging is a natural process that determined by a functional decline in cells and tissues as
organisms are growing old, resulting in an increase at risk of disease and death. To this end …

Osteoarthritis (OA) is an age-related metabolic disease. Low-grade inflammation and
oxidative stress are the last common pathway of OA. α-ketoglutarate (α-KG) is an essential …

Branched-chain amino acid transaminase 1 (BCAT1) is upregulated selectively in human
isocitrate dehydrogenase (IDH) wildtype (WT) but not mutant glioblastoma multiforme (GBM) …

In swine production, stress is a common encounter that leads to serious bacterial infection
and adverse effects on growth performance. Though antibiotics have been frequently used …

Background Great progress has been made in applying immunotherapy to the clinical
treatment of tumors. However, many patients with triple-negative breast cancer (TNBC) …

Alginate oligosaccharide is a kind of prebiotic with broad application prospects. However,
little attention is paid to the recovery effect of alginate oligosaccharide on disordered …

On average, aging is associated with unfavorable changes in cellular metabolism, which are
the processes involved in the storage and expenditure of energy. However, metabolic …

Osteoporosis (OP), which largely increases the risk of fractures, is the most common chronic
degenerative orthopedic disease in the elderly due to the imbalance of bone homeostasis …

Parkinson's disease (PD) is a progressive movement disorder characterized by
dopaminergic (DA) neuron degeneration and the existence of Lewy bodies formed by …