Inflammatory responses, manifested in excessive oxidative stress and microglia
overactivation, together with metal ion-triggered amyloid-beta (Aβ) deposition, are critical …

The predictive map hypothesis is a promising candidate principle for hippocampal function.
A favoured formalisation of this hypothesis, called the successor representation, proposes …

Associative memories guide behavioural adaptation by binding together outcome-predictive
sensory stimuli,. However, in a feature-rich environment, only a subset of stimuli may predict …

A brain-targeting nanodelivery system has been a hot topic and has undergone rapid
progression. However, due to various obstacles such as the intestinal epithelial barrier (IEB) …

The subregions of the entorhinal cortex (EC) are conventionally thought to compute
dichotomous representations for spatial processing, with the medial EC (MEC) providing a …

The hippocampus is the brain's center for episodic memories. Its subregions, the dentate
gyrus and CA1-3, are differentially involved in memory encoding and recall. Hippocampal …

In understanding circuit operations, a key problem is the extent to which neuronal spiking
reflects local computation or responses to upstream inputs. We addressed this issue in the …

Hippocampal subfield CA3 is thought to stably store memories in assemblies of recurrently
connected cells functioning as a collective. However, the collective hippocampal coding …

How do we recollect specific events that have occurred during continuous ongoing
experience? There is converging evidence from non-human animals that spatially …

Pulmonary arterial hypertension (PAH) is a chronic cardiopulmonary syndrome with high
pulmonary vascular load and eventually causing RV heart failure even death. However, the …