Contaminated water and food are the main sources of lead, cadmium, and mercury in the
human body. Long-term and low-level ingestion of these toxic heavy metals may affect brain …

Summary Representation of the environment by hippocampal populations is known to drift
even within a familiar environment, which could reflect gradual changes in single-cell activity …

Visual virtual reality (VR) systems for head-fixed mice offer advantages over real-world
studies for investigating the neural circuitry underlying behavior. However, current VR …

The representation of distinct spaces by hippocampal place cells has been linked to
changes in their place fields (the locations in the environment where the place cells …

Place cells establish rapid mapping relationships between the external environment and
themselves in a new context. However, the mapping relationships of environmental cues to …

Animals behave in multisensory environments guided by various modalities of spatial
information. Mammalian navigation engages a cognitive map of space in the hippocampus …

Abstract N 6-methyladenosine (m6A) has been demonstrated to regulate learning and
memory in mice. To investigate the mechanism by which m6A modification exerts its function …

Dynamic interactions between the subregions of the hippocampus are required for the
encoding and consolidation of memory. While the interplay and contributions of the CA1 and …

Cognitive maps confer animals with flexible intelligence by representing spatial, temporal,
and abstract relationships that can be used to shape thought, planning, and behavior …

Spatial navigation (SN) has been reported to be one of the first cognitive domains to be
affected in Alzheimer's disease (AD), which occurs as a result of progressive …