A consistent map in the medial entorhinal cortex supports spatial memory

TJ Malone, NW Tien, Y Ma, L Cui, S Lyu… - Nature …, 2024 - nature.com
The medial entorhinal cortex (MEC) is hypothesized to function as a cognitive map for
memory-guided navigation. How this map develops during learning and influences memory …

Long-term transverse imaging of the hippocampus with glass microperiscopes

WT Redman, NS Wolcott, L Montelisciani, G Luna… - Elife, 2022 - elifesciences.org
The hippocampus consists of a stereotyped neuronal circuit repeated along the septal-
temporal axis. This transverse circuit contains distinct subfields with stereotyped connectivity …

Transformer as a hippocampal memory consolidation model based on NMDAR-inspired nonlinearity

DK Kim, J Kwon, M Cha, C Lee - Advances in Neural …, 2024 - proceedings.neurips.cc
The hippocampus plays a critical role in learning, memory, and spatial representation,
processes that depend on the NMDA receptor (NMDAR). Inspired by recent findings that …

Subtle visual change in a virtual environment induces heterogeneous remapping systematically in CA1, but not CA3

J Shin, HW Lee, SW Jin, I Lee - Cell Reports, 2022 - cell.com
Environmental change may lead to new memories or modify old ones, but the underlying
neural mechanisms are largely unclear. We recorded hippocampal place cells …

High-frequency oscillations and sequence generation in two-population models of hippocampal region CA1

W Braun, RM Memmesheimer - PLOS Computational Biology, 2022 - journals.plos.org
Hippocampal sharp wave/ripple oscillations are a prominent pattern of collective activity,
which consists of a strong overall increase of activity with superimposed (140− 200 Hz) …

Global remapping in granule cells and mossy cells of the mouse dentate gyrus

SH Kim, D GoodSmith, SJ Temme, F Moriya, G Ming… - Cell reports, 2023 - cell.com
Hippocampal place cells exhibit spatially modulated firing, or place fields, which can remap
to encode changes in the environment or other variables. Unique among hippocampal …

Retuning of hippocampal representations during sleep

K Maboudi, B Giri, H Miyawaki, C Kemere, K Diba - Nature, 2024 - nature.com
Hippocampal representations that underlie spatial memory undergo continuous refinement
following formation. Here, to track the spatial tuning of neurons dynamically during offline …

Pathway-specific TNF-mediated metaplasticity in hippocampal area CA1

A Singh, S Sateesh, OD Jones, WC Abraham - Scientific reports, 2022 - nature.com
Long-term potentiation (LTP) is regulated in part by metaplasticity, the activity-dependent
alterations in neural state that coordinate the direction, amplitude, and persistence of future …

Calcium imaging reveals fast tuning dynamics of hippocampal place cells and CA1 population activity during free exploration task in mice

VP Sotskov, NA Pospelov, VV Plusnin… - International journal of …, 2022 - mdpi.com
Hippocampal place cells are a well-known object in neuroscience, but their place field
formation in the first moments of navigating in a novel environment remains an ill-defined …

[HTML][HTML] Distinct catecholaminergic pathways projecting to hippocampal CA1 transmit contrasting signals during behavior and learning

CM Heer, EJ Mark - bioRxiv, 2023 - ncbi.nlm.nih.gov
Neuromodulatory inputs to the hippocampus play pivotal roles in modulating synaptic
plasticity, shaping neuronal activity, and influencing learning and memory. Recently it has …