Discrimination and generalization, crucial brain-wide functions for memory and object
recognition, utilize pattern separation and completion computations. Circuit mechanisms …

To guide action, animals anticipate what events will occur, and when they will occur, based
on experience. How animals anticipate future events is an unsettled question. Although …

Background The hippocampus supports a multiplicity of functions, with the dorsal region
contributing to memory-related spatial representations, while the ventral hippocampus (vH) …

Principles governing the encoding, storage, and updating of memories in cortical networks
are poorly understood. In retrosplenial cortex (RSC), cells respond to the animal's position …

Anatomically segregated apical and basal dendrites of pyramidal neurons receive
functionally distinct inputs, but it is unknown if this results in compartment-level functional …

Spatial memories are represented by hippocampal place cells during navigation. This
spatial code is dynamic, undergoing changes across time–known as drift–and across …

Alzheimer's disease (AD) is a progressive, currently irreversible neurodegenerative disease
that causes significant deficits in cognition, learning, and memory. Though significant …

Dopaminergic activity in the hippocampus modulates synaptic plasticity, alters place cell
activity, and affects hippocampal dependent learning and memory processes. Traditionally …

When exploring new environments animals form spatial memories that are updated with
experience and retrieved upon re-exposure to the same environment. The hippocampus is …

The way we process the environment depends on ongoing internal activity within our brains.
The hippocampus is a brain region proposed to be involved in spatial navigation and …