The overall objective of this thesis is to elucidate previously unexplored nuances of
hippocampal network communication while providing novel experimental and computational …

In bilaterians organism, the signaling of pyramidal neurons (PyrNs) is linked to the relative
(prevalent) molecular chirality and physiological, perceptual, cognitive, and psychological …

Einleitung 2 cognitive impairment (milde kognitive Beeinträchtigung)(MCI). Dabei sind vor
allem Gedächtnis-und Exekutivfunktionen, Aufmerksamkeit, Sprache und die visuell …

Spatial navigation and path integration impairments are sensitive markers of pathological
decline during the early stages of Alzheimer's disease (AD). To investigate the neural circuit …

In the rodent hippocampus, spatial pathways are represented by the sequential activation of
multiple place cells, each corresponding to a specific location. This activation pattern …

The hippocampus is known to play a role in encoding, consolidating, updating and retrieving
episodic memories. But the mechanism underlying these processes remains unclear. My …

When exploring new environments, animals form spatial memories that are updated with
experience and retrieved upon re-exposure to the same environment. Coordinated …

The CA1 region of the hippocampus is thought to be involved in learning, memory, and
spatial navigation. Within the CA1 region, many pyramidal neurons have been identified as …

The hippocampal formation takes a leading part in spatial navigation and episodic memory.
Many decades of research revealed prominent neurons with salient responses, in particular …

During learning, the hippocampus is proposed to link the distributed components of
neocortical memory representations to a spatiotemporal framework. However, the continued …