[HTML][HTML] Therapeutics for COVID-19 and post COVID-19 complications: An update

D Basu, VP Chavda, AA Mehta - Current Research in Pharmacology and …, 2022 - Elsevier
Since its inception in late December 2020 in China, novel coronavirus has affected the
global socio-economic aspect. Currently, the world is seeking safe and effective treatment …

In vitro and in vivo models for studying SARS-CoV-2, the etiological agent responsible for COVID-19 pandemic

RB Rosa, WM Dantas, JCF do Nascimento… - Viruses, 2021 - mdpi.com
The emergence and rapid worldwide spread of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has prompted the scientific community to rapidly develop in …

Attenuation of clinical and immunological outcomes during SARS‐CoV‐2 infection by ivermectin

GD de Melo, F Lazarini, F Larrous, L Feige… - EMBO molecular …, 2021 - embopress.org
The devastating pandemic due to SARS‐CoV‐2 and the emergence of antigenic variants
that jeopardize the efficacy of current vaccines create an urgent need for a comprehensive …

Identification of novel inhibitors for SARS-CoV-2 as therapeutic options using machine learning-based virtual screening, molecular docking and MD simulation

A Samad, A Ajmal, A Mahmood, B Khurshid… - Frontiers in Molecular …, 2023 - frontiersin.org
The new coronavirus SARS-COV-2, which emerged in late 2019 from Wuhan city of China
was regarded as causing agent of the COVID-19 pandemic. The primary protease which is …

[HTML][HTML] Repositioning Ivermectin for Covid-19 treatment: Molecular mechanisms of action against SARS-CoV-2 replication

ZY Low, AJW Yip, SK Lal - Biochimica et Biophysica Acta (BBA)-Molecular …, 2022 - Elsevier
Ivermectin (IVM) is an FDA approved macrocyclic lactone compound traditionally used to
treat parasitic infestations and has shown to have antiviral potential from previous in-vitro …

Developing a multiepitope vaccine for the prevention of SARS-CoV-2 and monkeypox virus co-infection: a reverse vaccinology analysis

F Jiang, Y Liu, Y Xue, P Cheng, J Wang, J Lian… - International …, 2023 - Elsevier
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and
monkeypox virus (MPXV) severely threaten human health; however, currently, no vaccine …

COVID-19–associated rhino-orbital-cerebral mucormycosis: A systematic review, meta-analysis, and meta-regression analysis

A Bhattacharyya, P Sarma, H Kaur… - Indian Journal of …, 2021 - journals.lww.com
BACKGROUND: Till now, no meta-analysis is available to address the clinical profile, risk
factors, different interventions, and outcomes among COVID-19–associated rhino-orbito …

RETRACTED: effects of a single dose of ivermectin on viral and clinical outcomes in asymptomatic SARS-CoV-2 infected subjects: a pilot clinical trial in Lebanon

AA Samaha, H Mouawia, M Fawaz, H Hassan… - Viruses, 2021 - mdpi.com
Objective: This study was designed to determine the efficacy of ivermectin, an FDA-
approved drug, in producing clinical benefits and decreasing the viral load of SARS-CoV-2 …

Sialylated glycan bindings from SARS-CoV-2 spike protein to blood and endothelial cells govern the severe morbidities of COVID-19

DE Scheim, P Vottero, AD Santin, AG Hirsh - International journal of …, 2023 - mdpi.com
Consistent with well-established biochemical properties of coronaviruses, sialylated glycan
attachments between SARS-CoV-2 spike protein (SP) and host cells are key to the virus's …

[HTML][HTML] Ivermectin prophylaxis used for COVID-19: a citywide, prospective, observational study of 223,128 subjects using propensity score matching

L Kerr, FA Cadegiani, F Baldi, RB Lobo, WLO Assagra… - Cureus, 2022 - ncbi.nlm.nih.gov
Background: Ivermectin has demonstrated different mechanisms of action that potentially
protect from both coronavirus disease 2019 (COVID-19) infection and COVID-19-related …