Ischaemic and hypoxic conditioning: potential for protection of vital organs

JD Sprick, RT Mallet, K Przyklenk… - Experimental …, 2019 - Wiley Online Library
New Findings What is the topic of this review? Remote ischaemic preconditioning (RIPC)
and hypoxic preconditioning as novel therapeutic approaches for cardiac and …

[HTML][HTML] Peripheral mechanisms of ischemic myalgia

LF Queme, JL Ross, MP Jankowski - Frontiers in cellular …, 2017 - frontiersin.org
Musculoskeletal pain due to ischemia is present in a variety of clinical conditions including
peripheral vascular disease (PVD), sickle cell disease (SCD), complex regional pain …

Exaggerated cardiovascular responses to muscle contraction and tendon stretch in UCD type-2 diabetes mellitus rats

AK Grotle, CK Crawford, Y Huo… - American Journal …, 2019 - journals.physiology.org
Patients with type-2 diabetes mellitus (T2DM) have exaggerated sympathetic activity and
blood pressure responses to exercise. However, the underlying mechanisms for these …

Blood pressure and leg deoxygenation are exaggerated during treadmill walking in patients with peripheral artery disease

AJ Miller, JC Luck, DJK Kim… - Journal of Applied …, 2017 - journals.physiology.org
The purpose of this study was to investigate blood pressure (BP) and leg skeletal muscle
oxygen saturation (Smo2) during treadmill walking in patients with peripheral artery disease …

Exaggerated exercise pressor reflex in type 2 diabetes: potential role of oxidative stress

AK Grotle, AJ Stone - Autonomic Neuroscience, 2019 - Elsevier
Type 2 diabetes mellitus (T2DM) leads to exaggerated cardiovascular responses to
exercise, in part due to an exaggerated exercise pressor reflex. Accumulating data suggest …

Characteristics of acid‐sensing ion channel currents in male rat muscle dorsal root ganglion neurons following ischemia/reperfusion

Q Li, L Qin, J Li - Physiological reports, 2023 - Wiley Online Library
Peripheral artery diseases (PAD) increases muscle afferent nerve‐activated reflex
sympathetic nervous and blood pressure responses during exercise (termed as exercise …

Temporal changes in the exercise pressor reflex in type 1 diabetic rats

AK Grotle, EA Garcia, Y Huo… - American Journal of …, 2017 - journals.physiology.org
Previous studies have shown that diabetic peripheral neuropathy affects both unmyelinated
and myelinated afferents, similar to those evoking the exercise pressor reflex. However, the …

Aging exaggerates blood pressure response to ischemic rhythmic handgrip exercise in humans

D Hasegawa, A Hori, Y Okamura, R Baba… - Physiological …, 2021 - Wiley Online Library
Ischemic skeletal muscle conditions are known to augment exercise‐induced increases in
blood pressure (BP). Aging is also a factor that enhances the pressor response to exercise …

Muscle metaboreflex and cerebral blood flow regulation in humans: implications for exercise with blood flow restriction

E Prodel, GM Balanos, ID Braz… - American Journal …, 2016 - journals.physiology.org
We investigated the effect of activating metabolically sensitive skeletal muscle afferents
(muscle metaboreflex) on cerebral blood flow and the potentially confounding influence of …

Chronic femoral artery ligation exaggerates the pressor and sympathetic nerve responses during dynamic skeletal muscle stretch in decerebrate rats

EA Kempf, KS Rollins, TD Hopkins… - American Journal …, 2018 - journals.physiology.org
Mechanical and metabolic signals arising during skeletal muscle contraction reflexly
increase sympathetic nerve activity and blood pressure (ie, the exercise pressor reflex). In a …