Importance Sickle cell disease (SCD) is an inherited disorder of hemoglobin, characterized
by formation of long chains of hemoglobin when deoxygenated within capillary beds …

Cannabinoid co-administration may enable reduced opioid doses for analgesia. This
updated systematic review on the opioid-sparing effects of cannabinoids considered …

Significant changes have occurred in the policy landscape surrounding cannabis
legalization, production, and use around the globe and across the United States. With …

There has been an increased interest of the scientific community in cannabis and its
constituents for therapeutic purposes. Although it is believed that cannabinoids can be …

Cannabis has long been regarded as a recreational substance in the Western world. The
recent marketing authorization of some medicinal products of industrial origin and the …

Objectives To assess the benefits and harms of cannabinoids in participants with pain.
Design Systematic review of randomised clinical trials with meta-analysis, Trial Sequential …

The use of cannabis products to help with sleep and various other medical conditions by the
public has increased significantly in recent years. Withdrawal from cannabinoids can lead to …

Cannabinoids are lipophilic substances derived from Cannabis sativa that can exert a
variety of effects in the human body. They have been studied in cellular and animal models …

Pain is a major comorbidity of sickle cell disease (SCD). Patients with SCD may suffer from
both acute and chronic pain. Acute pain is caused by recurrent and unpredictable episodes …

Although descriptions of quality of life and patient reports of mood in sickle cell disease
(SCD) have become more common in the literature, less is known about psychiatric illness …