SARS-CoV-2 evolution in the Omicron era
C Roemer, DJ Sheward, R Hisner, F Gueli… - Nature …, 2023 - nature.com
Abstract Since SARS-CoV-2 BA. 5 (Omicron) emerged and spread in 2022, Omicron
lineages have markedly diversified. Here we review the evolutionary trajectories and …
lineages have markedly diversified. Here we review the evolutionary trajectories and …
[HTML][HTML] Broadly neutralizing antibodies against COVID-19
The COVID-19 pandemic caused by SARS-CoV-2 has led to hundreds of millions of
infections and millions of deaths, however, human monoclonal antibodies (mAbs) can be an …
infections and millions of deaths, however, human monoclonal antibodies (mAbs) can be an …
Convergent evolution of SARS-CoV-2 XBB lineages on receptor-binding domain 455–456 synergistically enhances antibody evasion and ACE2 binding
F Jian, L Feng, S Yang, Y Yu, L Wang, W Song… - PLoS …, 2023 - journals.plos.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) XBB lineages have
achieved dominance worldwide and keep on evolving. Convergent evolution of XBB …
achieved dominance worldwide and keep on evolving. Convergent evolution of XBB …
The SARS-CoV-2 neutralizing antibody response to SD1 and its evasion by BA. 2.86
Under pressure from neutralising antibodies induced by vaccination or infection the SARS-
CoV-2 spike gene has become a hotspot for evolutionary change, leading to the failure of all …
CoV-2 spike gene has become a hotspot for evolutionary change, leading to the failure of all …
Antigenicity assessment of SARS-CoV-2 saltation variant BA. 2.87. 1
S Yang, Y Yu, F Jian, A Yisimayi, W Song… - Emerging Microbes & …, 2024 - Taylor & Francis
The recent emergence of a SARS-CoV-2 saltation variant, BA. 2.87. 1, which features 65
spike mutations relative to BA. 2, has attracted worldwide attention. In this study, we …
spike mutations relative to BA. 2, has attracted worldwide attention. In this study, we …
Emerging variants develop total escape from potent monoclonal antibodies induced by BA. 4/5 infection
The rapid evolution of SARS-CoV-2 is driven in part by a need to evade the antibody
response in the face of high levels of immunity. Here, we isolate spike (S) binding …
response in the face of high levels of immunity. Here, we isolate spike (S) binding …
Unraveling the Dynamics of Omicron (BA. 1, BA. 2, and BA. 5) Waves and Emergence of the Deltacron Variant: Genomic Epidemiology of the SARS-CoV-2 Epidemic …
AC Chrysostomou, B Vrancken, C Haralambous… - Viruses, 2023 - mdpi.com
Commencing in December 2019 with the emergence of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), three years of the coronavirus disease 2019 (COVID-19) …
coronavirus 2 (SARS-CoV-2), three years of the coronavirus disease 2019 (COVID-19) …
Identification of a highly conserved neutralizing epitope within the RBD region of diverse SARS-CoV-2 variants
Y Wang, A Yan, D Song, M Duan, C Dong… - Nature …, 2024 - nature.com
The constant emergence of SARS-CoV-2 variants continues to impair the efficacy of existing
neutralizing antibodies, especially XBB. 1.5 and EG. 5, which showed exceptional immune …
neutralizing antibodies, especially XBB. 1.5 and EG. 5, which showed exceptional immune …
A structure-function analysis shows SARS-CoV-2 BA. 2.86 balances antibody escape and ACE2 affinity
Summary BA. 2.86, a recently described sublineage of SARS-CoV-2 Omicron, contains
many mutations in the spike gene. It appears to have originated from BA. 2 and is distinct …
many mutations in the spike gene. It appears to have originated from BA. 2 and is distinct …
A high-fidelity DNAzyme-assisted CRISPR/Cas13a system with single-nucleotide resolved specificity
Y Wu, R Jin, Y Chang, M Liu - Chemical Science, 2024 - pubs.rsc.org
A CRISPR/Cas system represents an innovative tool for developing a new-generation
biosensing and diagnostic strategy. However, the off-target issue (ie, mistaken cleavage of …
biosensing and diagnostic strategy. However, the off-target issue (ie, mistaken cleavage of …