Epilepsy and brain network hubs

J Royer, BC Bernhardt, S Larivière, E Gleichgerrcht… - …, 2022 - Wiley Online Library
Epilepsy is a disorder of brain networks. A better understanding of structural and dynamic
network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are …

Neurobehavioural comorbidities of epilepsy: towards a network-based precision taxonomy

BP Hermann, AF Struck, RM Busch, A Reyes… - Nature Reviews …, 2021 - nature.com
Cognitive and behavioural comorbidities are prevalent in childhood and adult epilepsies
and impose a substantial human and economic burden. Over the past century, the classic …

Defining epileptogenic networks: contribution of SEEG and signal analysis

F Bartolomei, S Lagarde, F Wendling, A McGonigal… - …, 2017 - Wiley Online Library
Epileptogenic networks are defined by the brain regions involved in the production and
propagation of epileptic activities. In this review we describe the historical, methodologic …

Seizures and epilepsy: an overview for neuroscientists

CE Stafstrom, L Carmant - Cold Spring …, 2015 - perspectivesinmedicine.cshlp.org
Epilepsy is one of the most common and disabling neurologic conditions, yet we have an
incomplete understanding of the detailed pathophysiology and, thus, treatment rationale for …

Modern network science of neurological disorders

CJ Stam - Nature Reviews Neuroscience, 2014 - nature.com
Modern network science has revealed fundamental aspects of normal brain-network
organization, such as small-world and scale-free patterns, hierarchical modularity, hubs and …

[HTML][HTML] The virtual epileptic patient: individualized whole-brain models of epilepsy spread

VK Jirsa, T Proix, D Perdikis, MM Woodman, H Wang… - Neuroimage, 2017 - Elsevier
Individual variability has clear effects upon the outcome of therapies and treatment
approaches. The customization of healthcare options to the individual patient should …

Individual brain structure and modelling predict seizure propagation

T Proix, F Bartolomei, M Guye, VK Jirsa - Brain, 2017 - academic.oup.com
Abstract See Lytton (doi: 10.1093/awx018) for a scientific commentary on this article. Neural
network oscillations are a fundamental mechanism for cognition, perception and …

Interictal stereotactic-EEG functional connectivity in refractory focal epilepsies

S Lagarde, N Roehri, I Lambert, A Trebuchon… - Brain, 2018 - academic.oup.com
Drug-refractory focal epilepsies are network diseases associated with functional connectivity
alterations both during ictal and interictal periods. A large majority of studies on the …

Connectome biomarkers of drug‐resistant epilepsy

S Lariviere, A Bernasconi, N Bernasconi… - …, 2021 - Wiley Online Library
Drug‐resistant epilepsy (DRE) considerably affects patient health, cognition, and well‐
being, and disproportionally contributes to the overall burden of epilepsy. The most common …

Structural connectivity differences in left and right temporal lobe epilepsy

P Besson, V Dinkelacker, R Valabregue, L Thivard… - Neuroimage, 2014 - Elsevier
Our knowledge on temporal lobe epilepsy (TLE) with hippocampal sclerosis has evolved
towards the view that this syndrome affects widespread brain networks. Diffusion weighted …