Favipiravir at high doses has potent antiviral activity in SARS-CoV-2− infected hamsters, whereas hydroxychloroquine lacks activity
SJF Kaptein, S Jacobs, L Langendries… - Proceedings of the …, 2020 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly spread around the
globe after its emergence in Wuhan in December 2019. With no specific therapeutic and …
globe after its emergence in Wuhan in December 2019. With no specific therapeutic and …
Molecular determinants and mechanism for antibody cocktail preventing SARS-CoV-2 escape
Antibody cocktails represent a promising approach to prevent SARS-CoV-2 escape. The
determinants for selecting antibody combinations and the mechanism that antibody cocktails …
determinants for selecting antibody combinations and the mechanism that antibody cocktails …
[HTML][HTML] A simple protein-based surrogate neutralization assay for SARS-CoV-2
KT Abe, Z Li, R Samson, P Samavarchi-Tehrani… - JCI insight, 2020 - ncbi.nlm.nih.gov
Most of the patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) mount a humoral immune response to the virus within a few weeks of infection, but …
CoV-2) mount a humoral immune response to the virus within a few weeks of infection, but …
Aptamer blocking strategy inhibits SARS‐CoV‐2 virus infection
M Sun, S Liu, X Wei, S Wan, M Huang… - Angewandte Chemie …, 2021 - Wiley Online Library
The COVID‐19 pandemic caused by SARS‐CoV‐2 is threating global health. Inhibiting
interaction of the receptor‐binding domain of SARS‐CoV‐2 S protein (SRBD) and human …
interaction of the receptor‐binding domain of SARS‐CoV‐2 S protein (SRBD) and human …
SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity
MG Joyce, WH Chen, RS Sankhala, A Hajduczki… - Cell reports, 2021 - cell.com
The need for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) next-
generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the …
generation vaccines has been highlighted by the rise of variants of concern (VoCs) and the …
A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate
The expanding pandemic of coronavirus disease 2019 (COVID-19) requires the
development of safe, efficacious and fast-acting vaccines. Several vaccine platforms are …
development of safe, efficacious and fast-acting vaccines. Several vaccine platforms are …
[HTML][HTML] Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies
Immediately from the outset of the COVID-19 pandemic, researchers from diverse
biomedical and biological disciplines have united to study the novel pandemic virus, SARS …
biomedical and biological disciplines have united to study the novel pandemic virus, SARS …
Close relatives of MERS-CoV in bats use ACE2 as their functional receptors
Q Xiong, L Cao, C Ma, MA Tortorici, C Liu, J Si, P Liu… - Nature, 2022 - nature.com
Middle East respiratory syndrome coronavirus (MERS-CoV) and several bat coronaviruses
use dipeptidyl peptidase-4 (DPP4) as an entry receptor,,–. However, the receptor for …
use dipeptidyl peptidase-4 (DPP4) as an entry receptor,,–. However, the receptor for …
Development of spirulina for the manufacture and oral delivery of protein therapeutics
The use of the edible photosynthetic cyanobacterium Arthrospira platensis (spirulina) as a
biomanufacturing platform has been limited by a lack of genetic tools. Here we report …
biomanufacturing platform has been limited by a lack of genetic tools. Here we report …
[HTML][HTML] Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) mediates
viral entry into cells and is critical for vaccine development against coronavirus disease …
viral entry into cells and is critical for vaccine development against coronavirus disease …