COVID-19 coagulopathy: from pathogenesis to treatment

T Alnima, MMG Mulder, BCT van Bussel… - Acta …, 2022 - karger.com
Abstract Coronavirus disease 2019 (COVID-19) has emerged as a pandemic at the end of
2019 and continues to exert an unfavorable worldwide health impact on a large proportion …

Studying the coagulopathy of COVID-19

AC Spyropoulos, MP Bonaca - The Lancet, 2022 - thelancet.com
The coagulopathy caused by SARS-CoV-2 seen in patients hospitalised with COVID-19,
especially those with severe or critical illness, is by now well established. Early reports in …

[HTML][HTML] Effect of weight-adjusted intermediate-dose versus fixed-dose prophylactic anticoagulation with low-molecular-weight heparin on venous thromboembolism …

S Zuily, B Lefèvre, O Sanchez, OE de Vendin… - …, 2023 - thelancet.com
Background Venous thromboembolism is a major complication of coronavirus disease 2019
(COVID-19). We hypothesized that a weight-adjusted intermediate dose of anticoagulation …

[HTML][HTML] Anticoagulation in COVID-19

CA Bradbury, Z McQuilten - The Lancet, 2022 - thelancet.com
vaccine effectiveness in terms of protection against actual infection; instead, effectiveness
was inferred from immunogenicity. Cellular immunity was only studied in 60% of the …

Heparin-induced thrombocytopenia in patients with COVID-19: a systematic review and meta-analysis

N Uaprasert, N Tangcheewinsirikul… - Blood …, 2021 - ashpublications.org
Heparin thromboprophylaxis is routinely administered during hospitalization for COVID-19.
Because of the immune stimulation related to COVID-19, there is ongoing concern regarding …

[HTML][HTML] Fundamentals in COVID-19-associated thrombosis: molecular and cellular aspects

DM Mizurini, ED Hottz, PT Bozza… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus disease (COVID-19) is associated with a high incidence of
coagulopathy and venous thromboembolism that may contribute to the worsening of the …

Anticoagulants for thrombosis prophylaxis in acutely ill patients admitted to hospital: systematic review and network meta-analysis

RJ Eck, T Elling, AJ Sutton, J Wetterslev, C Gluud… - bmj, 2022 - bmj.com
Objective To assess the benefits and harms of different types and doses of anticoagulant
drugs for the prevention of venous thromboembolism in patients who are acutely ill and …

[HTML][HTML] Anti-viral treatment for SARS-CoV-2 infection: A race against time amidst the ongoing pandemic

NG Vallianou, D Tsilingiris, GS Christodoulatos… - Metabolism open, 2021 - Elsevier
Αbstract Remdesivir (GS-5734), a drug initially developed to treat hepatitis C and Ebola
virus disease, was the first approved treatment for severe coronavirus disease 2019 (COVID …

[HTML][HTML] Practical recommendations for optimal thromboprophylaxis in patients with COVID-19: a consensus statement based on available clinical trials

KG Kyriakoulis, E Dimakakos, IG Kyriakoulis… - Journal of Clinical …, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) has been shown to be strongly associated with
increased risk for venous thromboembolism events (VTE) mainly in the inpatient but also in …

[HTML][HTML] Risk factors for venous thromboembolism in severe COVID-19: a study-level meta-analysis of 21 studies

H Lobbes, S Mainbourg, V Mai, M Douplat… - International Journal of …, 2021 - mdpi.com
Venous thromboembolism (VTE) in patients with COVID-19 in intensive care units (ICU) is
frequent, but risk factors (RF) remain unidentified. In this meta-analysis (CRD42020188764) …