Numerous age-dependent alterations at the molecular, cellular, tissue and organ systems
levels underlie the pathophysiology of aging. Herein, the focus is upon the secreted protein …

Occupational exposure to whole‐body vibration is associated with the development of
musculoskeletal, neurological, and other ailments. Low back pain and other spine disorders …

Skeletal muscle mass and function tend to decline with increasing age. Insulin-like growth
factor 1 (IGF-1) plays a key role in promoting skeletal muscle growth. Exercise improves …

Conditions of extended bed rest and limb immobilization can initiate rapid and significant
loss of skeletal muscle mass and function. Physical rehabilitation is standard practice …

Physical inactivity-induced atrophy of skeletal muscle Page 1 199 Abstract. – OBJECTIVE:
Long-term physical inactivity can cause the atrophy of skeletal muscle. The aim of this study is …

Objective The aim of the study was to examine how mechanical unloading affects articular
cartilage degeneration in the patellofemoral (PF) and tibiofemoral (TF) joints of a …

Background The aim of this study is to clarify the following two points: First, whether a
cyclooxygenase-2 mediated pathway is involved in the formation of immobilization-induced …

Extended bed rest or limb immobilization can significantly reduce skeletal muscle mass and
function. Recovery may be incomplete, particularly in older adults. Our laboratory recently …

Investigations into physiologically controlled capillary regression report the provocative
finding that microvessel regression occurs in the face of persistent elevation of skeletal …

Although morphological abnormalities of the femur are known predisposing factors for
numerous musculoskeletal disorders, the etiology of these abnormalities is poorly …