Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Mechanisms of 3-Hydroxyl 3-Methylglutaryl CoA Reductase in Alzheimer's Disease

X Zhou, X Wu, R Wang, L Han, H Li… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is the most common neurodegenerative disease worldwide and
has a high incidence in the elderly. Unfortunately, there is no effective therapy for AD owing …

Single-cell histone chaperones patterns guide intercellular communication of tumor microenvironment that contribute to breast cancer metastases

J Xie, W Deng, X Deng, JY Liang, Y Tang… - Cancer Cell …, 2023 - Springer
Abstract Background Histone chaperones (HCs) are crucial for governing genome stability
and gene expression in multiple cancers. However, the functioning of HCs in the tumor …

LncRNA-HOXC-AS2 regulates tumor-associated macrophage polarization through the STAT1/SOCS1 and STAT1/CIITA pathways to promote the progression of non …

C Yin, J Li, S Li, X Yang, Y Lu, C Wang, B Liu - Cellular Signalling, 2024 - Elsevier
Tumor-associated macrophages (TAMs) mainly exhibit the characteristics of M2-type
macrophages, and the regulation of TAM polarization is a new target for cancer therapy …

Exploring the Therapeutic Potential of Ammodaucus leucotrichus Seed Extracts: A Multi-Faceted Analysis of Phytochemical Composition, Anti-Inflammatory Efficacy …

C Djehiche, N Benzidane, H Djeghim, M Tebboub… - Pharmaceuticals, 2024 - mdpi.com
Ammodaucus leucotrichus exhibits promising pharmacological activity, hinting at anti-
inflammatory and anti-arthritic effects. This study investigated seed extracts from …

Probiotics in Wound Healing

VA Bădăluță, C Curuțiu, LM Dițu… - International Journal of …, 2024 - mdpi.com
Wound infections caused by opportunistic bacteria promote persistent infection and
represent the main cause of delayed healing. Probiotics are acknowledged for their …

What could be the function of the spinal muscular atrophy-causing protein SMN in macrophages?

I Tapken, NT Detering, P Claus - Frontiers in Immunology, 2024 - frontiersin.org
Spinal Muscular Atrophy (SMA), a neurodegenerative disorder, extends its impact beyond
the nervous system. The central protein implicated in SMA, Survival Motor Neuron (SMN) …

TYK2 Inhibitors for Treating Autoimmune and Inflammatory Diseases

RW Sabnis - ACS Medicinal Chemistry Letters, 2024 - ACS Publications
TYK2 Inhibitors for Treating Autoimmune and Inflammatory Diseases Page 1 TYK2
Inhibitors for Treating Autoimmune and Inflammatory Diseases Ram W. Sabnis* Cite This …

[HTML][HTML] Non-Coding RNA in Tumor Cells and Tumor-Associated Myeloid Cells—Function and Therapeutic Potential

AK Binder, F Bremm, J Dörrie, N Schaft - International Journal of …, 2024 - mdpi.com
The RNA world is wide, and besides mRNA, there is a variety of other RNA types, such as
non-coding (nc) RNAs, which harbor various intracellular regulatory functions. This review …

The Complex Interplay of Insulin Resistance and Metabolic Inflammation in Transition Dairy Cows

K Qiao, R Jiang, GA Contreras, L Xie, OB Pascottini… - Animals, 2024 - mdpi.com
Simple Summary This review critically examined the literature on the interaction between
insulin resistance (IR) and metabolic inflammation in transition dairy cows. Our review …