[HTML][HTML] Research Progress of Drug Delivery Systems Targeting the Kidneys

LF Huang, QR Ye, XC Chen, XR Huang, QF Zhang… - Pharmaceuticals, 2024 - mdpi.com
Chronic kidney disease (CKD) affects more than 10% of the global population, and its
incidence is increasing, partially due to an increase in the prevalence of disease risk factors …

[HTML][HTML] Integrated oral microgel system ameliorates renal fibrosis by hitchhiking co-delivery and targeted gut flora modulation

Y Hou, L Zhu, X Ye, Q Ke, Q Zhang, X Xie… - Journal of …, 2024 - Springer
Background Renal fibrosis is a progressive process associated with chronic kidney disease
(CKD), contributing to impaired kidney function. Active constituents in traditional Chinese …

[HTML][HTML] Impaired TFEB-mediated autophagy-lysosome fusion promotes tubular cell cycle G2/M arrest and renal fibrosis by suppressing ATP6V0C expression and …

X Ren, J Wang, H Wei, X Li, Y Tian… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Increasing evidence suggests that autophagy plays a major role during renal fibrosis.
Transcription factor EB (TFEB) is a critical regulator of autophagy-and lysosome-related …