Malaria is a mosquito-borne disease caused by parasites of the obligate intracellular
Apicomplexa phylum the most deadly of which, Plasmodium falciparum, prevails in Africa …

All the symptoms and pathology of malaria are caused by the intraerythrocytic stages of the
Plasmodium parasite life cycle. Because Plasmodium parasites cannot replicate outside a …

Antigenic diversity has posed a critical barrier to vaccine development against the
pathogenic blood-stage infection of the human malaria parasite Plasmodium falciparum. To …

Numerous efforts to understand the functional roles of antibodies demonstrated that they can
protect against malaria. However, it is unclear which antibody responses are the best …

Plasmodium parasites are the causative agent of human malaria, and the development of a
highly effective vaccine against infection, disease and transmission remains a key priority. It …

Background. Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) is a
blood-stage parasite protein essential for host erythrocyte invasion. PfRH5-specific …

Despite ongoing efforts, a highly effective vaccine against Plasmodium falciparum remains
elusive. Vaccines targeting the pre-erythrocytic stages of the P. falciparum life cycle are the …

There have been significant decreases in malaria mortality and morbidity in the last 10-15
years, and the most advanced pre-erythrocytic malaria vaccine, RTS, S, received a positive …

Host–parasite interactions that guide red blood cell invasio... : Current Opinion in
Hematology Host–parasite interactions that guide red blood cell invasion by malaria …

A highly-effective, long-lasting vaccine, targeting multiple stages of the Plasmodium
falciparum life cycle, is likely to be important for the elimination of this pathogen. Key …