[HTML][HTML] Inactivation of Mst/Nrf2/Keap1 signaling flexibly mitigates MAPK/NQO-HO1 activation in the reproductive axis of experimental fluorosis

MM Ommati, S Sabouri, Z Sun, MJ Zamiri… - Ecotoxicology and …, 2024 - Elsevier
Fluoride induced reprotoxicity through oxidative stress-mediated reproductive cell death.
Hence, the current study evaluated the importance of the MST/Nrf2/MAPK/NQO-HO1 …

[HTML][HTML] SIRT1, a target of miR-708-3p, alleviates fluoride-induced neuronal damage via remodeling mitochondrial network dynamics

Q Zhao, G Zhou, Q Niu, J Chen, P Li, Z Tian, D Li… - Journal of Advanced …, 2023 - Elsevier
Introduction Neurological dysfunction induced by fluoride contamination is still one of major
concern worldwide. Recently, neuroprotective roles of silent information regulator 1 (SIRT1) …

[HTML][HTML] The interaction between miRNAs and hazardous materials

S Ghafouri-Fard, H Shoorei, SD Oskuei… - Non-coding RNA …, 2023 - Elsevier
Toxic agents are broadly present in the environment, households, and workplaces.
Contamination of food and drinking water with these agents results in entry of these …

α-Lipoic acid improves mitochondrial biogenesis and dynamics by enhancing antioxidant and inhibiting Wnt/Ca2+ pathway to relieve fluoride-induced hepatotoxic …

Y Yu, J Xu, H Li, J Lv, Y Zhang, R Niu, J Wang… - Chemico-Biological …, 2023 - Elsevier
Fluoride (F), widely present in water and food, poses a serious threat to liver health, and
oxidative damage and mitochondrial damage are its main causes. As a natural …

Soybean meal peptide Gly-Thr-Tyr-Trp could protect mice from acute alcoholic liver damage: A study of protein-protein interaction and proteomic analysis

S Lyu, Z Cai, Q Yang, J Liu, Y Yu, F Pan, T Zhang - Food Chemistry, 2024 - Elsevier
Alcoholic liver disease (ALD) is a serious health threat. Soybean meal peptide (SMP)
supplementation may protect against this damage; however, the potential mechanism …

MiRNA-seq and mRNA-seq revealed the mechanism of fluoride-induced cauda epididymal injury

Y Yu, R Zhu, M Qi, J Liu, K Cao, D Zhang… - Science of The Total …, 2024 - Elsevier
The widespread presence of fluoride in water, food, and the environment continues to
exacerbate the impact of fluoride on the male reproductive health. However, as a critical …

Expression of SDF-1/CXCR4 and related inflammatory factors in sodium fluoride-treated hepatocytes

R Yang, H Shen, M Wang, Y Zhao, S Zhu, H Jiang, Y Li… - Plos one, 2024 - journals.plos.org
At present, the mechanism of fluorosis-induced damage to the hepatic system is unclear.
Studies have shown that excess fluoride causes some degree of damage to the liver …

Hairpin self-assembly powered by exonuclease III for highly sensitive and cross-validated miRNA-155 detection

J Ji, J Xu, S Wang, Q Wang, H Li - Analytical Methods, 2024 - pubs.rsc.org
Cancer is one of the most important causes of human death and poses a serious threat to
human health. As a cancer biomarker, microRNA-155 (miRNA-155) is highly expressed in …

[HTML][HTML] IL-17A基因敲除对氟诱导小鼠肝炎症反应和肝细胞凋亡的影响

赵阳飞, 于洋欢, 王金明, 张建海, 孙子龙, 牛瑞燕… - 畜牧兽医学报, 2023 - html.rhhz.net
畜禽水和食物中广泛存在的氟严重威胁着畜禽的肝健康和动物性食品的安全.
为阐明氟致肝损伤的内在机制, 明确IL-17A 在氟诱导肝炎症反应和肝细胞凋亡中的调节作用 …

The Effect of a Static Magnetic Field on microRNA in Relation to the Regulation of the Nrf2 Signaling Pathway in a Fibroblast Cell Line That Had Been Treated with …

M Kimsa-Dudek, A Krawczyk… - Applied Sciences, 2023 - mdpi.com
Many physical and chemical factors can influence the Nrf2 signaling pathway, and its
deregulation has been associated with various disease states. Nrf2 and Keap1 molecules …