Sickle cell disease (SCD) is a group of inherited autosomal recessive disorders, including
sickle cell anemia, sickle beta-thalassemia, and other hemoglobinopathies, which are …

Health‐related quality of life (HRQL) is defined as the patient's appraisal of how his/her well
being and level of functioning, compared to the perceived ideal, are affected by individual …

Study objective We provide an updated assessment of trends in sickle cell disease (SCD)–
related mortality, a significant source of mortality in the United States among black persons …

Pain in sickle cell disease (SCD) is associated with increased morbidity, mortality, and high
health care costs. Although episodic acute pain is the hallmark of this disorder, there is an …

Abstract Sickle Cell Anemia (SCA) is a hereditary blood disorder that affects millions of
people worldwide, predominantly of African descent. While the physical aspects of SCA …

Sickle cell disease (SCD) is a chronic, debilitating disorder. Chronically ill patients are at risk
for depression, which can affect health-related quality of life (HRQoL), health care utilization …

Abstract Adults with Sickle Cell Disease (SCD) experience multiple disease-related
complications, but few studies have examined relationships between these events and …

Patients with sickle cell disease (SCD) experience a disproportionately high use of health
care resources. Several studies have examined depression and other negative mood states …

Sickle cell disease (SCD), which affects approximately 100,000 individuals in the USA and
more than 3 million worldwide, is caused by mutations in the βb globin gene that result in …

Background Sleep disturbance and depression are commonly encountered in primary care.
In sickle cell disease, depression is associated with pain, poor treatment compliance, and …