Oxidative stress (OS) has greatly interested the research community in understanding
damaging processes occurring in cells. OS is triggered by an imbalance between reactive …

Resveratrol increases the production of nitric oxide (NO) in endothelial cells by upregulating
the expression of endothelial NO synthase (eNOS), stimulating eNOS enzymatic activity, and …

Increasing evidence from epidemiological, clinical and experimental studies indicate that
age-related cerebromicrovascular dysfunction and microcirculatory damage play critical …

The antioxidant effects of resveratrol (3, 5, 4'‐trihydroxy‐trans‐stilbene) contribute
substantially to the health benefits of this compound. Resveratrol has been shown to be a …

Resveratrol, a natural polyphenolic compound, is found in various kinds of fruits, plants, and
their commercial products such as red wine. It has been demonstrated to exhibit a variety of …

The vascular endothelium is a multifunctional organ and is critically involved in modulating
vascular tone and structure. Endothelial cells produce a wide range of factors that also …

Resveratrol is a polyphenol that plays a potentially important role in many disorders and has
been studied in different diseases. The research on this chemical started through the …

A small molecule that safely mimics the ability of dietary restriction (DR) to delay age-related
diseases in laboratory animals is greatly sought after. We and others have shown that …

Epidemiological studies suggest that Mediterranean diets rich in resveratrol are associated
with reduced risk of coronary artery disease. Resveratrol was also shown to confer …

This review focuses on molecular, cellular, and functional changes that occur in the
vasculature during aging; explores the links between mitochondrial oxidative stress …