Determinants of passive antibody efficacy in SARS-CoV-2 infection

E Stadler, KL Chai, TE Schlub, D Cromer… - MedRxiv, 2022 - medrxiv.org
Background A large number of studies have been carried out involving passive antibody
administration for the treatment and prophylaxis of COVID-19 and have shown variable …

COVID-19 treatments: then and now

SS Mustafa, RA Stern, PC Patel, DK Chu - The Journal of Allergy and …, 2023 - Elsevier
The coronavirus disease 2019 (COVID-19) pandemic has evolved over the past 3+ years,
and strategies to prevent illness and treat infection have changed over time. As COVID-19 …

Clinical update on COVID-19 for the emergency and critical care clinician: Medical management

B Long, S Chavez, BM Carius, WJ Brady… - The American Journal of …, 2022 - Elsevier
Introduction Coronavirus disease of 2019 (COVID-19) has resulted in millions of cases
worldwide. As the pandemic has progressed, the understanding of this disease has evolved …

Association of mortality and early tracheostomy in patients with COVID-19: a retrospective analysis

AN Flinspach, H Booke, K Zacharowski, Ü Balaban… - Scientific reports, 2022 - nature.com
COVID-19 adds to the complexity of optimal timing for tracheostomy. Over the course of this
pandemic, and expanded knowledge of the disease, many centers have changed their …

COVID-19 prophylaxis in immunosuppressed patients: Beyond vaccination

I Gentile, N Schiano Moriello - PLoS Medicine, 2022 - journals.plos.org
COVID-19 prophylaxis in immunosuppressed patients: Beyond vaccination | PLOS Medicine
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The efficiency of convalescent plasma in COVID-19 patients: A systematic review and meta-analysis of randomized controlled clinical trials

Z Qian, Z Zhang, H Ma, S Shao, H Kang… - Frontiers in …, 2022 - frontiersin.org
The objective of this study was to assess whether convalescent plasma therapy could offer
survival advantages for patients with novel coronavirus disease 2019 (COVID-19). An …

Efficacy of high-dose polyclonal intravenous immunoglobulin in COVID-19: A systematic review

D Focosi, M Franchini, M Tuccori, M Cruciani - Vaccines, 2022 - mdpi.com
Background: Although several therapeutic strategies have been investigated, the optimal
treatment approach for patients with coronavirus disease (COVID-19) remains to be …

Effectiveness of mid-regional pro-adrenomedullin, compared to other biomarkers (including lymphocyte subpopulations and immunoglobulins), as a prognostic …

G Montrucchio, G Sales, E Balzani, D Lombardo… - Frontiers in …, 2023 - frontiersin.org
Background Mid-regional pro-adrenomedullin (MR-proADM), an endothelium-related
peptide, is a predictor of death and multi-organ failure in respiratory infections and sepsis …

[PDF][PDF] Determinants of passive antibody effectiveness in SARS-CoV-2 infection

E Stadler, KL Chai, TE Schlub, D Cromer… - medrxiv, 2022 - scholar.archive.org
Neutralising antibodies are an important correlate of protection from SARS-CoV-2 infection.
Multiple studies have investigated the effectiveness of passively administered antibodies …

Three out of four published systematic reviews on COVID-19 treatments were not registered and one-third of those registered were published: a meta-research study

W Siemens, J Nothacker, J Stadelmaier… - Journal of Clinical …, 2022 - Elsevier
Objectives The aim of this study is to describe (1) registered and (2) published systematic
reviews (SRs) on COVID-19 treatments, and to analyze (3) the proportion of publications …